Elvitegravir, Cobicistat, Emtricitabine, / Tenofovir Disoproxil Fumarate

Common brands: Stribild, Truvada, Viread, Complera, Genvoya

Top reporter: Gilead Sciences, Inc.

Cytochrome P450 3A Inhibitor [EPC]Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor [EPC]Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]Protease Inhibitor [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]
8,938
Total Reports
4,323
Serious Reports
140
Death Reports
30
Reported Reactions
Death Report Ratio: Moderate (1.57%)

Patient Demographics

Male
5,941
Female
1,985

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Elvitegravir, Cobicistat, Emtricitabine, / Tenofovir Disoproxil Fumarate.

# Reaction Reports % of Total
1 BONE DENSITY DECREASED 4,571
11.2%
2 RENAL INJURY 3,305
8.1%
3 SKELETAL INJURY 3,021
7.4%
4 CHRONIC KIDNEY DISEASE 2,494
6.1%
5 TOOTH LOSS 2,465
6.0%
6 BONE LOSS 2,141
5.3%
7 OSTEONECROSIS 2,101
5.2%
8 RENAL FAILURE 2,067
5.1%
9 TOOTH INJURY 1,971
4.8%
10 MULTIPLE FRACTURES 1,965
4.8%
11 PAIN 1,843
4.5%
12 EMOTIONAL DISTRESS 1,810
4.4%
13 OSTEOPOROSIS 1,737
4.3%
14 ANXIETY 1,692
4.2%
15 ANHEDONIA 1,634
4.0%
16 OSTEOPENIA 1,079
2.6%
17 ECONOMIC PROBLEM 679
1.7%
18 ACUTE KIDNEY INJURY 597
1.5%
19 BLOOD CREATININE INCREASED 542
1.3%
20 RENAL IMPAIRMENT 478
1.2%
21 VITAMIN D DEFICIENCY 401
1.0%
22 NEPHROPATHY 346
0.8%
23 FRACTURE 300
0.7%
24 DEPRESSION 288
0.7%
25 BONE DENSITY ABNORMAL 276
0.7%
26 BONE DISORDER 216
0.5%
27 FOOT FRACTURE 205
0.5%
28 TOOTH FRACTURE 188
0.5%
29 OSTEOARTHRITIS 178
0.4%
30 BONE DEMINERALISATION 174
0.4%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.