FDA Adverse Event Reports,
Made Searchable

Explore reported side effects for 788 drugs based on 41,500,301 adverse event reports from the FDA's FAERS database.

Browse All Drugs Browse Reactions
788
Drugs Tracked
300
Adverse Reactions
41,500,301
Total Reports

Most Reported Drugs

Drugs with the highest number of adverse event reports in the FDA FAERS database.

Drug Generic Name Reports Serious Deaths Top Reaction
Adalimumab ADALIMUMAB 699,270 199,753 29,476 DRUG INEFFECTIVE
Etanercept ETANERCEPT 592,886 68,976 16,796 DRUG INEFFECTIVE
Aspirin ASPIRIN 526,243 179,760 48,450 FATIGUE
Prednisone PREDNISONE 491,127 211,610 51,085 DRUG INEFFECTIVE
Dupilumab DUPILUMAB 438,499 371,681 1,972 PRURITUS
Acetaminophen ACETAMINOPHEN 435,016 228,218 61,374 DRUG INEFFECTIVE
Lenalidomide LENALIDOMIDE 414,399 164,687 53,306 DIARRHOEA
Methotrexate METHOTREXATE 413,991 134,588 33,134 DRUG INEFFECTIVE
Furosemide FUROSEMIDE 392,821 143,376 61,227 DYSPNOEA
Ergocalciferol ERGOCALCIFEROL 374,010 136,380 22,203 FATIGUE
Gabapentin GABAPENTIN 357,299 121,051 33,770 DRUG INEFFECTIVE
Metformin METFORMIN 348,087 129,185 29,280 NAUSEA
Omeprazole OMEPRAZOLE 336,750 115,760 30,779 FATIGUE
Levothyroxine LEVOTHYROXINE SODIUM 308,080 88,909 19,965 FATIGUE
Lisinopril LISINOPRIL 300,893 81,219 24,957 FATIGUE
Dexamethasone DEXAMETHASONE 290,332 132,070 47,003 OFF LABEL USE
Pregabalin PREGABALIN 267,194 74,618 21,597 DRUG INEFFECTIVE
Ibuprofen IBUPROFEN 266,217 88,406 17,983 DRUG INEFFECTIVE
Amlodipine AMLODIPINE 263,058 104,046 29,131 FATIGUE
Metoprolol METOPROLOL 249,388 84,883 28,411 FATIGUE
Simvastatin SIMVASTATIN 247,115 52,686 22,054 FATIGUE
Pain Reliever PAIN RELIEVER 247,093 154,926 49,065 OFF LABEL USE
Pantoprazole PANTOPRAZOLE 245,972 119,741 27,811 FATIGUE
Folic Acid FOLIC ACID 244,564 82,880 22,646 DRUG INEFFECTIVE
Atorvastatin ATORVASTATIN CALCIUM 242,941 60,908 18,534 FATIGUE
Insulin Glargine INSULIN GLARGINE 240,130 78,659 13,381 BLOOD GLUCOSE INCREASED
Infliximab INFLIXIMAB 214,259 66,277 13,350 DRUG INEFFECTIVE
Rituximab RITUXIMAB 205,592 109,381 36,036 OFF LABEL USE
Rivaroxaban RIVAROXABAN 205,037 61,389 26,972 GASTROINTESTINAL HAEMORRHAGE
Alprazolam ALPRAZOLAM 202,859 68,488 33,238 DRUG INEFFECTIVE
Rosuvastatin ROSUVASTATIN 198,883 70,158 11,958 FATIGUE
Levonorgestrel LEVONORGESTREL 198,676 33,742 267 DEVICE EXPULSION
Denosumab DENOSUMAB 198,109 63,625 25,330 OFF LABEL USE
Ranitidine RANITIDINE 197,543 59,829 15,476 BREAST CANCER
Ibupfrofen IBUPFROFEN 195,031 72,831 15,945 DRUG INEFFECTIVE
Clopidogrel CLOPIDOGREL 194,883 54,042 21,618 DYSPNOEA
Interferon Beta-1a INTERFERON BETA-1A 191,752 21,708 9,759 MULTIPLE SCLEROSIS RELAPSE
Quetiapine QUETIAPINE 188,606 71,209 27,635 DRUG INEFFECTIVE
Oxycodone OXYCODONE 183,089 110,139 52,276 DRUG DEPENDENCE
Tofacitinib TOFACITINIB 182,680 77,994 8,918 DRUG INEFFECTIVE
Adapalene ADAPALENE 180,881 17,556 32 DRUG INEFFECTIVE
Natalizumab NATALIZUMAB 180,087 21,803 5,066 FATIGUE
Lorazepam LORAZEPAM 176,559 62,549 25,411 FATIGUE
Prednisolone PREDNISOLONE 176,266 77,522 28,237 OFF LABEL USE
Lansoprazole LANSOPRAZOLE 175,048 53,602 19,613 CHRONIC KIDNEY DISEASE
Cyclophosphamide CYCLOPHOSPHAMIDE 172,252 92,096 35,010 OFF LABEL USE
Cyclophosphamide For CYCLOPHOSPHAMIDE FOR INJECTION 172,252 92,095 35,010 OFF LABEL USE
Losartan LOSARTAN 169,596 67,909 12,337 FATIGUE
Secukinumab SECUKINUMAB 158,767 68,217 8,114 DRUG INEFFECTIVE
Clonazepam CLONAZEPAM 157,187 50,718 18,448 DRUG INEFFECTIVE

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Most Reported Adverse Reactions

The most commonly reported side effects across all drugs in the FAERS database.

Reaction Total Reports Drugs Involved
DRUG INEFFECTIVE 3,105,678 729
FATIGUE 2,489,744 719
OFF LABEL USE 2,394,039 700
NAUSEA 2,239,650 737
DIARRHOEA 1,934,049 671
PAIN 1,918,498 624
HEADACHE 1,711,076 635
DYSPNOEA 1,698,664 633
VOMITING 1,285,499 647
ARTHRALGIA 1,261,559 420
DEATH 1,229,019 487
DIZZINESS 1,195,774 567
RASH 1,119,343 465
MALAISE 1,059,312 544
ASTHENIA 1,006,089 533
PNEUMONIA 988,504 484
PYREXIA 928,962 462
FALL 817,593 394
CONDITION AGGRAVATED 772,824 339
WEIGHT DECREASED 595,573 348
PAIN IN EXTREMITY 579,664 246
PRURITUS 577,023 264
RHEUMATOID ARTHRITIS 506,079 57
COUGH 492,083 249
ANXIETY 464,706 288
ACUTE KIDNEY INJURY 437,242 229
JOINT SWELLING 410,371 74
ALOPECIA 382,570 98
INSOMNIA 355,764 225
ANAEMIA 352,938 243

View all 300 reactions →

About This Data

This site uses data from the FDA Adverse Event Reporting System (FAERS) accessed via the openFDA API. Reports are submitted voluntarily and do not prove that a drug caused a side effect. A high number of reports may reflect widespread use rather than higher risk. This is not medical advice. Always consult your healthcare provider.