Tenofovir Disoproxil

Common brands: Viread, Truvada, Epivir, Lamivudine, Stribild

Top reporter: Gilead Sciences, Inc.

Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]Cytochrome P450 3A Inhibitor [EPC]Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]Protease Inhibitor [EPC]Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor [EPC]
32,755
Total Reports
13,488
Serious Reports
1,926
Death Reports
30
Reported Reactions
Death Report Ratio: High (5.88%)

Patient Demographics

Male
19,215
Female
9,213

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Tenofovir Disoproxil.

# Reaction Reports % of Total
1 BONE DENSITY DECREASED 10,655
10.5%
2 RENAL INJURY 9,278
9.1%
3 SKELETAL INJURY 8,329
8.2%
4 CHRONIC KIDNEY DISEASE 7,278
7.1%
5 OSTEONECROSIS 7,261
7.1%
6 BONE LOSS 7,071
6.9%
7 MULTIPLE FRACTURES 6,826
6.7%
8 RENAL FAILURE 6,678
6.6%
9 OSTEOPOROSIS 5,384
5.3%
10 TOOTH LOSS 4,514
4.4%
11 PAIN 3,037
3.0%
12 EMOTIONAL DISTRESS 2,858
2.8%
13 ANXIETY 2,675
2.6%
14 ANHEDONIA 2,458
2.4%
15 OSTEOPENIA 2,251
2.2%
16 TOOTH INJURY 2,009
2.0%
17 BLOOD CREATININE INCREASED 1,633
1.6%
18 RENAL IMPAIRMENT 1,522
1.5%
19 ACUTE KIDNEY INJURY 1,205
1.2%
20 NEPHROPATHY 1,064
1.0%
21 FOETAL EXPOSURE DURING PREGNANCY 921
0.9%
22 DRUG INEFFECTIVE 911
0.9%
23 ECONOMIC PROBLEM 905
0.9%
24 VIROLOGIC FAILURE 833
0.8%
25 FRACTURE 800
0.8%
26 PATHOGEN RESISTANCE 799
0.8%
27 DRUG RESISTANCE 739
0.7%
28 VIRAL MUTATION IDENTIFIED 733
0.7%
29 DEATH 598
0.6%
30 FATIGUE 586
0.6%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.