Buprenorphine

Common brands: Butrans, Oxycontin, Dilaudid, Ms Contin, Oxycodone Hydrochloride

Top reporter: Knoa Pharma Llc

Partial Opioid Agonist [EPC]Opioid Agonist [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]Benzodiazepine [EPC]Corticosteroid [EPC]
90,978
Total Reports
43,600
Serious Reports
26,053
Death Reports
30
Reported Reactions
Death Report Ratio: High (28.64%)

Patient Demographics

Male
27,577
Female
35,808

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Buprenorphine.

# Reaction Reports % of Total
1 DEATH 13,331
10.7%
2 DRUG DEPENDENCE 12,476
10.0%
3 OVERDOSE 10,937
8.7%
4 TOXICITY TO VARIOUS AGENTS 10,749
8.6%
5 PAIN 8,214
6.6%
6 DRUG WITHDRAWAL SYNDROME 6,935
5.5%
7 DRUG INEFFECTIVE 6,294
5.0%
8 EMOTIONAL DISTRESS 5,442
4.3%
9 NAUSEA 4,474
3.6%
10 DRUG ABUSE 3,683
2.9%
11 PRODUCT ADHESION ISSUE 3,301
2.6%
12 APPLICATION SITE RASH 3,050
2.4%
13 INADEQUATE ANALGESIA 3,036
2.4%
14 DIZZINESS 2,652
2.1%
15 RASH 2,537
2.0%
16 VOMITING 2,370
1.9%
17 APPLICATION SITE PRURITUS 2,352
1.9%
18 HEADACHE 2,326
1.9%
19 OFF LABEL USE 2,097
1.7%
20 FATIGUE 1,897
1.5%
21 DRUG WITHDRAWAL SYNDROME NEONATAL 1,765
1.4%
22 APPLICATION SITE ERYTHEMA 1,749
1.4%
23 DEPRESSION 1,744
1.4%
24 ANXIETY 1,733
1.4%
25 DYSPNOEA 1,717
1.4%
26 APPLICATION SITE IRRITATION 1,702
1.4%
27 DRUG EFFECT DECREASED 1,689
1.3%
28 MATERNAL EXPOSURE DURING PREGNANCY 1,687
1.3%
29 SOMNOLENCE 1,662
1.3%
30 CONFUSIONAL STATE 1,556
1.2%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.