Alteplase
Common brands: Activase, Cathflo Activase, Pain Relief, Medline, Tylenol Extra Strength
Top reporter: Genentech, Inc.
Nonsteroidal Anti-inflammatory Drug [EPC]Osmotic Laxative [EPC]Platelet Aggregation Inhibitor [EPC]Corticosteroid [EPC]Benzodiazepine [EPC]
14,763
Total Reports
8,006
Serious Reports
3,206
Death Reports
30
Reported Reactions
Death Report Ratio: High (21.72%)
Patient Demographics
Reported Adverse Reactions (30)
Side effects reported in FDA adverse event reports for Alteplase.
| # | Reaction | Reports | % of Total |
|---|---|---|---|
| 1 | NO ADVERSE EVENT | 2,489 | |
| 2 | OFF LABEL USE | 1,846 | |
| 3 | DEATH | 1,185 | |
| 4 | GINGIVAL BLEEDING | 1,020 | |
| 5 | CEREBRAL HAEMORRHAGE | 803 | |
| 6 | HAEMORRHAGE INTRACRANIAL | 726 | |
| 7 | DRUG INEFFECTIVE | 626 | |
| 8 | ANGIOEDEMA | 620 | |
| 9 | HAEMORRHAGE | 570 | |
| 10 | HAEMORRHAGIC TRANSFORMATION STROKE | 430 | |
| 11 | PRODUCT STORAGE ERROR | 381 | |
| 12 | NAUSEA | 363 | |
| 13 | HYPOTENSION | 343 | |
| 14 | DYSPNOEA | 339 | |
| 15 | VOMITING | 335 | |
| 16 | PNEUMONIA | 281 | |
| 17 | CHEST PAIN | 270 | |
| 18 | HEADACHE | 251 | |
| 19 | CEREBROVASCULAR ACCIDENT | 246 | |
| 20 | INTERCEPTED PRODUCT STORAGE ERROR | 245 | |
| 21 | INTERCEPTED MEDICATION ERROR | 244 | |
| 22 | PYREXIA | 242 | |
| 23 | CEREBRAL INFARCTION | 212 | |
| 24 | PAIN | 212 | |
| 25 | NEUROLOGICAL DECOMPENSATION | 195 | |
| 26 | RESPIRATORY FAILURE | 193 | |
| 27 | PULMONARY EMBOLISM | 192 | |
| 28 | ISCHAEMIC STROKE | 180 | |
| 29 | CARDIAC ARREST | 172 | |
| 30 | INTENTIONAL PRODUCT USE ISSUE | 171 |
Important Disclaimer
FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.