Cytarabine

Common brands: Methotrexate, Trexall, Jylamvo, Otrexup, Rasuvo

Top reporter: Fresenius Kabi Usa, Llc

Nucleoside Metabolic Inhibitor [EPC]Corticosteroid [EPC]Alkylating Drug [EPC]Folate Analog Metabolic Inhibitor [EPC]Topoisomerase Inhibitor [EPC]
58,625
Total Reports
31,834
Serious Reports
13,474
Death Reports
30
Reported Reactions
Death Report Ratio: High (22.98%)

Patient Demographics

Male
27,767
Female
20,095

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Cytarabine.

# Reaction Reports % of Total
1 FEBRILE NEUTROPENIA 7,495
11.2%
2 OFF LABEL USE 4,977
7.4%
3 PYREXIA 4,090
6.1%
4 NEUTROPENIA 3,636
5.4%
5 DRUG INEFFECTIVE 3,109
4.6%
6 SEPSIS 2,922
4.4%
7 THROMBOCYTOPENIA 2,897
4.3%
8 DISEASE PROGRESSION 2,732
4.1%
9 PNEUMONIA 2,301
3.4%
10 MYELOSUPPRESSION 2,088
3.1%
11 PANCYTOPENIA 2,085
3.1%
12 DEATH 2,027
3.0%
13 SEPTIC SHOCK 1,852
2.8%
14 NAUSEA 1,833
2.7%
15 INFECTION 1,817
2.7%
16 ANAEMIA 1,805
2.7%
17 DIARRHOEA 1,759
2.6%
18 PRODUCT USE IN UNAPPROVED INDICATION 1,755
2.6%
19 MUCOSAL INFLAMMATION 1,718
2.6%
20 VOMITING 1,715
2.6%
21 PLATELET COUNT DECREASED 1,637
2.4%
22 HYPOTENSION 1,464
2.2%
23 ACUTE MYELOID LEUKAEMIA 1,308
2.0%
24 WHITE BLOOD CELL COUNT DECREASED 1,251
1.9%
25 RESPIRATORY FAILURE 1,246
1.9%
26 BONE MARROW FAILURE 1,217
1.8%
27 ACUTE KIDNEY INJURY 1,212
1.8%
28 HEADACHE 1,042
1.6%
29 ABDOMINAL PAIN 1,002
1.5%
30 NEUTROPHIL COUNT DECREASED 961
1.4%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.