Etoposide

Common brands: Vepesid, Avopef, Cyclophosphamide, Frindovyx, Carboplatin

Top reporter: Amneal Pharmaceuticals Ny Llc

Topoisomerase Inhibitor [EPC]Alkylating Drug [EPC]Platinum-based Drug [EPC]Corticosteroid [EPC]Nucleoside Metabolic Inhibitor [EPC]
71,566
Total Reports
38,886
Serious Reports
17,502
Death Reports
30
Reported Reactions
Death Report Ratio: High (24.46%)

Patient Demographics

Male
33,376
Female
23,267

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Etoposide.

# Reaction Reports % of Total
1 OFF LABEL USE 8,003
9.7%
2 FEBRILE NEUTROPENIA 7,525
9.1%
3 NEUTROPENIA 4,984
6.0%
4 DRUG INEFFECTIVE 4,601
5.6%
5 DISEASE PROGRESSION 4,417
5.3%
6 THROMBOCYTOPENIA 4,002
4.8%
7 PYREXIA 3,368
4.1%
8 ANAEMIA 3,284
4.0%
9 SEPSIS 2,988
3.6%
10 PRODUCT USE IN UNAPPROVED INDICATION 2,939
3.6%
11 DEATH 2,808
3.4%
12 PANCYTOPENIA 2,694
3.3%
13 PNEUMONIA 2,459
3.0%
14 NAUSEA 2,417
2.9%
15 DIARRHOEA 2,266
2.7%
16 MUCOSAL INFLAMMATION 2,204
2.7%
17 VOMITING 2,117
2.6%
18 INFECTION 2,001
2.4%
19 MALIGNANT NEOPLASM PROGRESSION 1,942
2.4%
20 MYELOSUPPRESSION 1,855
2.2%
21 SEPTIC SHOCK 1,524
1.8%
22 DYSPNOEA 1,517
1.8%
23 FATIGUE 1,458
1.8%
24 PLATELET COUNT DECREASED 1,423
1.7%
25 ACUTE MYELOID LEUKAEMIA 1,422
1.7%
26 BONE MARROW FAILURE 1,351
1.6%
27 RESPIRATORY FAILURE 1,277
1.5%
28 LEUKOPENIA 1,268
1.5%
29 ACUTE KIDNEY INJURY 1,261
1.5%
30 WHITE BLOOD CELL COUNT DECREASED 1,251
1.5%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.