Ifosfamide

Common brands: Ifex, Vepesid, Avopef, Etoposide, Doxorubicin Hydrochloride

Top reporter: Baxter Healthcare Corporation

Alkylating Drug [EPC]Topoisomerase Inhibitor [EPC]Platinum-based Drug [EPC]Corticosteroid [EPC]CD20-directed Cytolytic Antibody [EPC]
20,887
Total Reports
11,089
Serious Reports
4,306
Death Reports
30
Reported Reactions
Death Report Ratio: High (20.62%)

Patient Demographics

Male
9,499
Female
6,828

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Ifosfamide.

# Reaction Reports % of Total
1 OFF LABEL USE 2,745
9.9%
2 FEBRILE NEUTROPENIA 2,639
9.5%
3 DISEASE PROGRESSION 2,089
7.5%
4 NEUTROPENIA 1,882
6.8%
5 DRUG INEFFECTIVE 1,557
5.6%
6 THROMBOCYTOPENIA 1,513
5.4%
7 ANAEMIA 1,229
4.4%
8 PYREXIA 978
3.5%
9 PRODUCT USE IN UNAPPROVED INDICATION 939
3.4%
10 SEPSIS 867
3.1%
11 INFECTION 795
2.9%
12 PANCYTOPENIA 763
2.7%
13 VOMITING 747
2.7%
14 NAUSEA 735
2.6%
15 MALIGNANT NEOPLASM PROGRESSION 717
2.6%
16 MUCOSAL INFLAMMATION 699
2.5%
17 DIARRHOEA 629
2.3%
18 ENCEPHALOPATHY 609
2.2%
19 DEATH 570
2.1%
20 MYELODYSPLASTIC SYNDROME 554
2.0%
21 CYTOPENIA 535
1.9%
22 MYELOSUPPRESSION 518
1.9%
23 ACUTE MYELOID LEUKAEMIA 509
1.8%
24 LEUKOPENIA 470
1.7%
25 PNEUMONIA 452
1.6%
26 ACUTE KIDNEY INJURY 439
1.6%
27 BONE MARROW FAILURE 422
1.5%
28 TOXICITY TO VARIOUS AGENTS 403
1.5%
29 ASPERGILLUS INFECTION 386
1.4%
30 PLATELET COUNT DECREASED 384
1.4%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.