Pegaspargase

Common brands: Oncaspar, Methotrexate, Jylamvo, Otrexup, Rasuvo

Top reporter: Servier Pharmaceuticals Llc

Asparagine-specific Enzyme [EPC]Corticosteroid [EPC]Folate Analog Metabolic Inhibitor [EPC]Nucleoside Metabolic Inhibitor [EPC]Alkylating Drug [EPC]
12,050
Total Reports
5,244
Serious Reports
1,540
Death Reports
30
Reported Reactions
Death Report Ratio: High (12.78%)

Patient Demographics

Male
4,590
Female
3,387

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Pegaspargase.

# Reaction Reports % of Total
1 FEBRILE NEUTROPENIA 1,573
12.4%
2 PYREXIA 767
6.0%
3 FEBRILE BONE MARROW APLASIA 676
5.3%
4 VOMITING 597
4.7%
5 NEUTROPENIA 569
4.5%
6 SEPSIS 561
4.4%
7 ABDOMINAL PAIN 508
4.0%
8 HYPOTENSION 462
3.6%
9 PANCREATITIS 411
3.2%
10 HYPERTRIGLYCERIDAEMIA 406
3.2%
11 THROMBOCYTOPENIA 402
3.2%
12 NAUSEA 400
3.1%
13 HYPERBILIRUBINAEMIA 367
2.9%
14 PNEUMONIA 360
2.8%
15 BACTERIAL INFECTION 339
2.7%
16 SEPTIC SHOCK 335
2.6%
17 OFF LABEL USE 331
2.6%
18 HYPERSENSITIVITY 330
2.6%
19 TACHYCARDIA 330
2.6%
20 MUCOSAL INFLAMMATION 328
2.6%
21 ANAEMIA 308
2.4%
22 HYPOFIBRINOGENAEMIA 299
2.4%
23 ALANINE AMINOTRANSFERASE INCREASED 273
2.1%
24 PANCYTOPENIA 273
2.1%
25 CLOSTRIDIUM DIFFICILE COLITIS 267
2.1%
26 VIRAL INFECTION 259
2.0%
27 HEADACHE 257
2.0%
28 ACUTE KIDNEY INJURY 246
1.9%
29 DIARRHOEA 245
1.9%
30 ANAPHYLACTIC REACTION 235
1.8%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.