Pemetrexed Disodium

Common brands: Pemetrexed, Axtle, Pemfexy, Carboplatin, Kyxata

Top reporter: Fresenius Kabi Usa, Llc

Platinum-based Drug [EPC]Folate Analog Metabolic Inhibitor [EPC]Programmed Death Receptor-1 Blocking Antibody [EPC]Vitamin B12 [EPC]Vitamin C [EPC]
36,708
Total Reports
20,401
Serious Reports
7,045
Death Reports
30
Reported Reactions
Death Report Ratio: High (19.19%)

Patient Demographics

Male
19,746
Female
13,543

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Pemetrexed Disodium.

# Reaction Reports % of Total
1 MALIGNANT NEOPLASM PROGRESSION 3,041
7.7%
2 OFF LABEL USE 2,267
5.8%
3 ANAEMIA 2,073
5.3%
4 NAUSEA 1,876
4.8%
5 DIARRHOEA 1,783
4.5%
6 PANCYTOPENIA 1,701
4.3%
7 NEUTROPENIA 1,689
4.3%
8 DEATH 1,668
4.2%
9 THROMBOCYTOPENIA 1,590
4.0%
10 FATIGUE 1,422
3.6%
11 VOMITING 1,395
3.5%
12 DISEASE PROGRESSION 1,370
3.5%
13 DYSPNOEA 1,303
3.3%
14 ACUTE KIDNEY INJURY 1,255
3.2%
15 PYREXIA 1,251
3.2%
16 RASH 1,222
3.1%
17 PNEUMONIA 1,216
3.1%
18 FEBRILE NEUTROPENIA 1,208
3.1%
19 ASTHENIA 1,154
2.9%
20 DRUG INEFFECTIVE 1,094
2.8%
21 DECREASED APPETITE 1,040
2.6%
22 GENERAL PHYSICAL HEALTH DETERIORATION 923
2.3%
23 INTERSTITIAL LUNG DISEASE 884
2.2%
24 MYELOSUPPRESSION 816
2.1%
25 PLATELET COUNT DECREASED 734
1.9%
26 PNEUMONITIS 733
1.9%
27 RENAL FAILURE 709
1.8%
28 PLEURAL EFFUSION 669
1.7%
29 DEHYDRATION 646
1.6%
30 PULMONARY EMBOLISM 645
1.6%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.