Siponimod

Common brands: Mayzent, Vitamin D, Baclofen, Baclofen (Intrathecal), Fleqsuvy

Top reporter: Novartis Pharmaceuticals Corporation

Sphingosine 1-phosphate Receptor Modulator [EPC]Provitamin D2 Compound [EPC]gamma-Aminobutyric Acid-ergic Agonist [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]Potassium Channel Blocker [EPC]
8,797
Total Reports
4,896
Serious Reports
206
Death Reports
30
Reported Reactions
Death Report Ratio: Moderate (2.34%)

Patient Demographics

Male
2,051
Female
6,159

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Siponimod.

# Reaction Reports % of Total
1 FATIGUE 989
8.5%
2 HEADACHE 888
7.6%
3 DIZZINESS 664
5.7%
4 GAIT DISTURBANCE 532
4.6%
5 MULTIPLE SCLEROSIS RELAPSE 532
4.6%
6 FALL 506
4.3%
7 MULTIPLE SCLEROSIS 484
4.1%
8 DRUG INEFFECTIVE 417
3.6%
9 LYMPHOCYTE COUNT DECREASED 415
3.6%
10 NAUSEA 415
3.6%
11 PRODUCT DOSE OMISSION ISSUE 391
3.3%
12 URINARY TRACT INFECTION 371
3.2%
13 COVID-19 365
3.1%
14 ASTHENIA 356
3.0%
15 PAIN 339
2.9%
16 BALANCE DISORDER 312
2.7%
17 HYPOAESTHESIA 308
2.6%
18 MALAISE 306
2.6%
19 MEMORY IMPAIRMENT 305
2.6%
20 FEELING ABNORMAL 291
2.5%
21 HYPERTENSION 287
2.5%
22 WHITE BLOOD CELL COUNT DECREASED 274
2.3%
23 VISUAL IMPAIRMENT 269
2.3%
24 PAIN IN EXTREMITY 254
2.2%
25 MUSCULAR WEAKNESS 243
2.1%
26 HEART RATE DECREASED 242
2.1%
27 PERIPHERAL SWELLING 240
2.1%
28 DYSPNOEA 238
2.0%
29 LYMPHOPENIA 225
1.9%
30 VISION BLURRED 225
1.9%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.