PAIN IN EXTREMITY

Adverse reaction reported in 579,664 FDA reports across 246 drugs.

579,664

Total Reports

246

Drugs Involved

Etanercept

Most Reported Drug

Drugs Associated with PAIN IN EXTREMITY

Drugs where "PAIN IN EXTREMITY" was reported as an adverse event.

#	Drug	Reports	% of Total
1	Etanercept	25,531	4.4%
2	Adalimumab	24,453	4.2%
3	Methotrexate	18,024	3.1%
4	Prednisone	16,943	2.9%
5	Ergocalciferol	14,646	2.5%
6	Acetaminophen	13,535	2.3%
7	Aspirin	13,009	2.2%
8	Gabapentin	11,496	2.0%
9	Pregabalin	11,283	1.9%
10	Folic Acid	10,680	1.8%
11	Tofacitinib	10,355	1.8%
12	Levothyroxine	9,723	1.7%
13	Furosemide	8,878	1.5%
14	Teriparatide	8,347	1.4%
15	Omeprazole	8,234	1.4%
16	Atorvastatin	8,233	1.4%
17	Lisinopril	7,759	1.3%
18	Metformin	7,706	1.3%
19	Ibuprofen	7,702	1.3%
20	Secukinumab	7,208	1.2%
21	Simvastatin	6,988	1.2%
22	Denosumab	6,950	1.2%
23	Calcium	6,922	1.2%
24	Rosuvastatin	6,877	1.2%
25	Alendronate	6,532	1.1%
26	Amlodipine	6,305	1.1%
27	Celecoxib	6,295	1.1%
28	Acetaminophen, Guaifenesin, / Phenylephrine Hydrochloride	6,293	1.1%
29	Metoprolol	5,917	1.0%
30	Ibupfrofen	5,842	1.0%
31	Interferon Beta-1a	5,035	0.9%
32	Natalizumab	4,923	0.8%
33	Treprostinil	4,830	0.8%
34	Losartan	4,824	0.8%
35	Hydrochlorothiazide	4,406	0.8%
36	Naproxen	4,404	0.8%
37	Clopidogrel	4,117	0.7%
38	Hydrocortisone	3,809	0.7%
39	Vitamin C	3,754	0.6%
40	Atenolol	3,751	0.6%
41	Ramipril	3,723	0.6%
42	Methylprednisolone	3,627	0.6%
43	Ciprofloxacin	3,617	0.6%
44	Evolocumab	3,416	0.6%
45	Tadalafil	3,342	0.6%
46	Magnesium	3,334	0.6%
47	Fish Oil	3,331	0.6%
48	Ambrisentan	3,120	0.5%
49	Citalopram	3,031	0.5%
50	Escitalopram	2,976	0.5%
51	Zolpidem	2,975	0.5%
52	Warfarin	2,963	0.5%
53	Albuterol	2,959	0.5%
54	Carvedilol	2,917	0.5%
55	Azathioprine	2,873	0.5%
56	Chloride	2,863	0.5%
57	Carbonate	2,799	0.5%
58	Upadacitinib	2,692	0.5%
59	Ciprofolxacin	2,668	0.5%
60	Baclofen	2,648	0.5%
61	Macitentan	2,643	0.5%
62	Valsartan	2,638	0.5%
63	Meloxicam	2,617	0.5%
64	Fingolimod	2,612	0.5%
65	Ezetimibe	2,392	0.4%
66	Loratadine	2,242	0.4%
67	Chloride Extended-	2,227	0.4%
68	Potassium Chloride, Dextrose Monohydrate	2,227	0.4%
69	Fluticasone	2,210	0.4%
70	Risedronate	2,160	0.4%
71	Antacid	2,158	0.4%
72	Morphine	2,143	0.4%
73	Selexipag	2,100	0.4%
74	Iron	2,022	0.3%
75	Estradiol	1,966	0.3%
76	Levofloxacin	1,933	0.3%
77	Levofloxacin In 5% Dextrose	1,933	0.3%
78	Clopidogrel Bisulfate	1,923	0.3%
79	Dalfampridine	1,845	0.3%
80	Sildenafil	1,820	0.3%
81	Cabozantinib	1,776	0.3%
82	Letrozole	1,771	0.3%
83	Drospirenone / Ethinyl Estradiol	1,757	0.3%
84	Capecitabine	1,751	0.3%
85	Duloxetine	1,747	0.3%
86	Cyclobenzaprine	1,704	0.3%
87	Candesartan	1,655	0.3%
88	Zoledronic Acid	1,646	0.3%
89	Teriflunomide	1,635	0.3%
90	Ocrelizumab	1,608	0.3%
91	Docusate	1,555	0.3%
92	Metoroprolol	1,523	0.3%
93	Diltiazem	1,467	0.3%
94	Octreotide	1,461	0.3%
95	Oxygen	1,455	0.3%
96	0xygen	1,454	0.3%
97	Etonogestrel	1,452	0.3%
98	Anastrozole	1,390	0.2%
99	Sunitinib Malate	1,330	0.2%
100	Glipizide	1,323	0.2%
101	Insulin Aspart	1,313	0.2%
102	Multivitamin	1,300	0.2%
103	Riociguat	1,299	0.2%
104	Estrogens, Conjugated	1,292	0.2%
105	Conjugated Estrogens	1,265	0.2%
106	Melatonin	1,261	0.2%
107	Insulin	1,237	0.2%
108	Vitamin E	1,237	0.2%
109	Enzalutamide	1,218	0.2%
110	Enalapril	1,214	0.2%
111	Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	1,206	0.2%
112	Lidocaine Hydrochloride / Epinephrine Bitartrate	1,191	0.2%
113	Leuprolide	1,179	0.2%
114	Risankizumab-Rzaa	1,177	0.2%
115	Ofatumumab	1,158	0.2%
116	Irbesartan	1,149	0.2%
117	Glatiramer	1,136	0.2%
118	Lidocaine, Menthol	1,136	0.2%
119	Ferrous	1,134	0.2%
120	Burn Relief	1,118	0.2%
121	Lidicaine	1,118	0.2%
122	Biotin	1,088	0.2%
123	Ribociclib	1,069	0.2%
124	Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol / Niacinamide	1,066	0.2%
125	Nifedipine	1,037	0.2%
126	Loperamide	1,037	0.2%
127	Temazepam	1,031	0.2%
128	Estradiol Transdermal	1,015	0.2%
129	Ascorbic Acid	1,006	0.2%
130	Ciprofloxacin Hydrochloride / Hydrocortisone	979	0.2%
131	Abaloparatide	974	0.2%
132	Cyanocobalamin	970	0.2%
133	Sorafenib	965	0.2%
134	Alirocumab	939	0.2%
135	Latanoprost	919	0.2%
136	Oxide	915	0.2%
137	Zinc Gluconate	899	0.2%
138	Dexlansoprazole	875	0.2%
139	Nilotinib	862	0.1%
140	Zinc Chloride	861	0.1%
141	Zinc	858	0.1%
142	Epoprostenol	845	0.1%
143	Cephalexin	803	0.1%
144	Methocarbamol	787	0.1%
145	Fenofibrate	786	0.1%
146	Regorafenib	770	0.1%
147	Belimumab	763	0.1%
148	Ibuprofen / Diphenhydramine Citrate	756	0.1%
149	Loperamide Hydrochloride / Dimethicone	752	0.1%
150	Lovastatin	750	0.1%
151	Candesartan Cilexetil	744	0.1%
152	Insulin Detemir	741	0.1%
153	Tizanidine	720	0.1%
154	Sumatriptan	716	0.1%
155	Raloxifene	716	0.1%
156	Rabeprazole	702	0.1%
157	Sennosides	697	0.1%
158	Glimepiride	696	0.1%
159	Pioglitazone	685	0.1%
160	Glyburide	656	0.1%
161	Colchicine	649	0.1%
162	Exemestane	648	0.1%
163	Carisoprodol	633	0.1%
164	Minocycline	586	0.1%
165	Doxazosin	583	0.1%
166	Oxybutynin	578	0.1%
167	Tamsulosin	573	0.1%
168	Nitrofurantoin (Monohydrate / Macrocrystals)	549	0.1%
169	Nitrofurantoin Monohydrate / Macrocrystals	549	0.1%
170	Ezetimibe / Simvastatin	548	0.1%
171	Nitrofurantoin	545	0.1%
172	Pravastatin	542	0.1%
173	Promethazine	542	0.1%
174	Insulin Glargine-Yfgn	537	0.1%
175	Meclizine	523	0.1%
176	Etonogestrel / Ethinyl Estradiol	517	0.1%
177	Hydroxyurea	508	0.1%
178	Asfotase Alfa	503	0.1%
179	Interferon Beta-1b	494	0.1%
180	Indomethacin	468	0.1%
181	Solifenacin	465	0.1%
182	Relugolix	462	0.1%
183	Naproxen Sodium, Pseudoephedrine Hydrochloride	456	0.1%
184	Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	456	0.1%
185	Gemfibrozil	456	0.1%
186	Axitinib	451	0.1%
187	Omega-3-Acid Ethyl Esters	446	0.1%
188	Dicyclomine	445	0.1%
189	Indapamide	437	0.1%
190	Erythropoietin	422	0.1%
191	Pramipexole	422	0.1%
192	Pazopanib	415	0.1%
193	Tolterodine	412	0.1%
194	Sitagliptin / Metformin Hydrochloride	406	0.1%
195	Clotrimazole	400	0.1%
196	Valsartan / Hydrochlorothiazide	392	0.1%
197	Drs Clotrimazole	378	0.1%
198	Family Wellness Clotrimazole	378	0.1%
199	Niacin	375	0.1%
200	Trazodone	368	0.1%
201	Diphenoxylate Hydrochloride / Atropine Sulfate	368	0.1%
202	Thiamine	358	0.1%
203	Eltrombopag Olamine	354	0.1%
204	Umeclidinium Bromide / Vilanterol Trifenatate	334	0.1%
205	Lidocaine Patch 5%	333	0.1%
206	Lapatinib	324	0.1%
207	Losartan Potassium / Hydrochlorothiazide	323	0.1%
208	Cholestyramine	322	0.1%
209	Butalbital, Acetaminophen, / Caffeine	320	0.1%
210	Agalsidase Beta	307	0.1%
211	Captopril	300	0.1%
212	Psyllium Husk	297	0.1%
213	Cefuroxime	295	0.1%
214	Lisinopril / Hydrochlorothiazide	288	0.0%
215	Human Insulin	287	0.0%
216	Romosozumab-Aqqg	286	0.0%
217	Acetaminophen, Aspirin, / Caffeine	283	0.0%
218	Amlodipine Besylate / Benazepril Hydrochloride	278	0.0%
219	Chlorthalidone	272	0.0%
220	Fesoterodine	268	0.0%
221	Clobetasol	266	0.0%
222	Clobetasol Propionate Ointment Usp, 0.05%	266	0.0%
223	Voxelotor	264	0.0%
224	Thyroid, Porcine	264	0.0%
225	Conjugated Estrogens / Medroxyprogesterone Acetate	260	0.0%
226	Hyoscyamine	259	0.0%
227	Epoetin Alfa	257	0.0%
228	Icosapent Ethyl	257	0.0%
229	Siponimod	254	0.0%
230	Peginterferon Beta-1a	247	0.0%
231	Quinine	244	0.0%
232	Colesevelam	239	0.0%
233	Amlodipine Besylate / Valsartan	238	0.0%
234	Desloratadine	231	0.0%
235	Terazosin	218	0.0%
236	Quinapril	216	0.0%
237	Oxybutynin Chloride	205	0.0%
238	Paricalcitol	196	0.0%
239	Fondaparinux	193	0.0%
240	Testosterone Cypionate	154	0.0%
241	Apalutamide	149	0.0%
242	Prasugrel	148	0.0%
243	Baricitinib	127	0.0%
244	Ozanimod	122	0.0%
245	Emicizumab	116	0.0%
246	Travoprost	108	0.0%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. The presence of a drug in this list does not mean the drug caused pain in extremity. Always consult your healthcare provider.