Carfilzomib

Common brands: Kyprolis, Maxidex, Dexamethasone 1.5 Mg, Hemady, Ozurdex

Top reporter: Onyx Pharmaceuticals, Inc.

Proteasome Inhibitor [EPC]Corticosteroid [EPC]Thalidomide Analog [EPC]CD38-directed Cytolytic Antibody [EPC]Alkylating Drug [EPC]
27,745
Total Reports
13,151
Serious Reports
4,329
Death Reports
30
Reported Reactions
Death Report Ratio: High (15.60%)

Patient Demographics

Male
12,313
Female
10,049

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Carfilzomib.

# Reaction Reports % of Total
1 PLASMA CELL MYELOMA 2,989
10.4%
2 OFF LABEL USE 2,359
8.2%
3 DEATH 1,757
6.1%
4 FATIGUE 1,529
5.3%
5 THROMBOCYTOPENIA 1,516
5.3%
6 PNEUMONIA 1,364
4.7%
7 PYREXIA 1,157
4.0%
8 DIARRHOEA 1,114
3.9%
9 DYSPNOEA 1,113
3.9%
10 ANAEMIA 1,104
3.8%
11 NEUTROPENIA 1,092
3.8%
12 NAUSEA 1,063
3.7%
13 ACUTE KIDNEY INJURY 854
3.0%
14 DRUG INEFFECTIVE 836
2.9%
15 ASTHENIA 705
2.5%
16 HYPERTENSION 704
2.4%
17 DISEASE PROGRESSION 687
2.4%
18 NEUROPATHY PERIPHERAL 681
2.4%
19 INFECTION 653
2.3%
20 PLATELET COUNT DECREASED 595
2.1%
21 SEPSIS 583
2.0%
22 CARDIAC FAILURE 548
1.9%
23 THERAPY PARTIAL RESPONDER 543
1.9%
24 VOMITING 524
1.8%
25 COVID-19 487
1.7%
26 RENAL FAILURE 465
1.6%
27 PANCYTOPENIA 443
1.5%
28 RASH 438
1.5%
29 MALAISE 433
1.5%
30 PLASMA CELL MYELOMA REFRACTORY 427
1.5%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.