Cyclophosphamide

Common brands: Frindovyx, Doxorubicin Hydrochloride, Rituxan, Prednisone Tablets, Usp, 10 Mg, Prednisone Tablets, Usp, 20 Mg

Top reporter: Avyxa Pharma, Llc

Alkylating Drug [EPC]Corticosteroid [EPC]CD20-directed Cytolytic Antibody [EPC]Nucleoside Metabolic Inhibitor [EPC]Topoisomerase Inhibitor [EPC]
172,252
Total Reports
92,096
Serious Reports
35,010
Death Reports
30
Reported Reactions
Death Report Ratio: High (20.32%)

Patient Demographics

Male
63,362
Female
75,791

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Cyclophosphamide.

# Reaction Reports % of Total
1 OFF LABEL USE 15,866
9.1%
2 FEBRILE NEUTROPENIA 14,218
8.2%
3 NEUTROPENIA 10,339
6.0%
4 DRUG INEFFECTIVE 10,333
6.0%
5 PYREXIA 9,062
5.2%
6 DISEASE PROGRESSION 7,924
4.6%
7 PNEUMONIA 6,512
3.8%
8 PRODUCT USE IN UNAPPROVED INDICATION 6,446
3.7%
9 THROMBOCYTOPENIA 6,347
3.7%
10 NAUSEA 6,104
3.5%
11 ANAEMIA 5,981
3.4%
12 SEPSIS 5,612
3.2%
13 DIARRHOEA 5,386
3.1%
14 DEATH 5,152
3.0%
15 VOMITING 4,799
2.8%
16 INFECTION 4,542
2.6%
17 PANCYTOPENIA 4,186
2.4%
18 FATIGUE 4,148
2.4%
19 WHITE BLOOD CELL COUNT DECREASED 4,146
2.4%
20 MYELOSUPPRESSION 4,137
2.4%
21 DYSPNOEA 3,739
2.2%
22 CYTOKINE RELEASE SYNDROME 3,632
2.1%
23 MUCOSAL INFLAMMATION 3,464
2.0%
24 NEUROPATHY PERIPHERAL 3,353
1.9%
25 PLATELET COUNT DECREASED 3,096
1.8%
26 ASTHENIA 3,082
1.8%
27 MALIGNANT NEOPLASM PROGRESSION 3,040
1.8%
28 RESPIRATORY FAILURE 2,996
1.7%
29 LEUKOPENIA 2,992
1.7%
30 SEPTIC SHOCK 2,985
1.7%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.