Doxorubicin

Common brands: Doxorubicin Hydrochloride, Cyclophosphamide, Frindovyx, Rituxan, Prednisone

Top reporter: Amneal Pharmaceuticals Llc

Alkylating Drug [EPC]Corticosteroid [EPC]CD20-directed Cytolytic Antibody [EPC]Topoisomerase Inhibitor [EPC]Platinum-based Drug [EPC]
86,429
Total Reports
47,108
Serious Reports
16,498
Death Reports
30
Reported Reactions
Death Report Ratio: High (19.09%)

Patient Demographics

Male
30,684
Female
35,973

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Doxorubicin.

# Reaction Reports % of Total
1 FEBRILE NEUTROPENIA 8,912
9.6%
2 OFF LABEL USE 8,648
9.3%
3 DISEASE PROGRESSION 6,354
6.9%
4 NEUTROPENIA 6,298
6.8%
5 DRUG INEFFECTIVE 5,092
5.5%
6 PYREXIA 3,981
4.3%
7 THROMBOCYTOPENIA 3,707
4.0%
8 ANAEMIA 3,704
4.0%
9 NAUSEA 3,100
3.3%
10 DEATH 3,075
3.3%
11 PRODUCT USE IN UNAPPROVED INDICATION 2,960
3.2%
12 PNEUMONIA 2,793
3.0%
13 SEPSIS 2,760
3.0%
14 DIARRHOEA 2,660
2.9%
15 VOMITING 2,543
2.7%
16 FATIGUE 2,194
2.4%
17 PANCYTOPENIA 2,148
2.3%
18 INFECTION 2,115
2.3%
19 MALIGNANT NEOPLASM PROGRESSION 2,082
2.2%
20 NEUROPATHY PERIPHERAL 2,061
2.2%
21 MUCOSAL INFLAMMATION 1,961
2.1%
22 DYSPNOEA 1,824
2.0%
23 LEUKOPENIA 1,691
1.8%
24 ALOPECIA 1,564
1.7%
25 SEPTIC SHOCK 1,530
1.7%
26 WHITE BLOOD CELL COUNT DECREASED 1,430
1.5%
27 ASTHENIA 1,429
1.5%
28 MYELOSUPPRESSION 1,414
1.5%
29 ACUTE KIDNEY INJURY 1,332
1.4%
30 TOXICITY TO VARIOUS AGENTS 1,332
1.4%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.