Fluorouracil Cream, 0.5%

Common brands: Fluorouracil, Efudex, Tolak, Oxaliplatin, Avastin

Top reporter: Dr. Reddy'S Laboratories Inc.

Nucleoside Metabolic Inhibitor [EPC]Platinum-based Drug [EPC]Vascular Endothelial Growth Factor Inhibitor [EPC]Epidermal Growth Factor Receptor Antagonist [EPC]Microtubule Inhibitor [EPC]
74,062
Total Reports
33,499
Serious Reports
10,606
Death Reports
30
Reported Reactions
Death Report Ratio: High (14.32%)

Patient Demographics

Male
34,840
Female
28,524

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Fluorouracil Cream, 0.5%.

# Reaction Reports % of Total
1 DIARRHOEA 6,774
9.0%
2 NEUTROPENIA 5,071
6.8%
3 NAUSEA 4,791
6.4%
4 VOMITING 3,868
5.2%
5 OFF LABEL USE 3,405
4.5%
6 NEUROPATHY PERIPHERAL 3,225
4.3%
7 DISEASE PROGRESSION 3,181
4.2%
8 FATIGUE 3,019
4.0%
9 PYREXIA 2,973
4.0%
10 THROMBOCYTOPENIA 2,906
3.9%
11 FEBRILE NEUTROPENIA 2,825
3.8%
12 ASTHENIA 2,503
3.3%
13 ANAEMIA 2,467
3.3%
14 DRUG INEFFECTIVE 2,143
2.9%
15 MALIGNANT NEOPLASM PROGRESSION 2,079
2.8%
16 DECREASED APPETITE 1,998
2.7%
17 DEATH 1,968
2.6%
18 DYSPNOEA 1,968
2.6%
19 ABDOMINAL PAIN 1,867
2.5%
20 MUCOSAL INFLAMMATION 1,779
2.4%
21 DEHYDRATION 1,676
2.2%
22 LEUKOPENIA 1,582
2.1%
23 STOMATITIS 1,508
2.0%
24 RASH 1,482
2.0%
25 GENERAL PHYSICAL HEALTH DETERIORATION 1,395
1.9%
26 PULMONARY EMBOLISM 1,383
1.8%
27 SEPSIS 1,370
1.8%
28 MYELOSUPPRESSION 1,240
1.7%
29 PNEUMONIA 1,221
1.6%
30 HYPERTENSION 1,184
1.6%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.