Melphalan

Common brands: Evomela, Maxidex, Dexamethasone, Dexamethasone 1.5 Mg, Dextenza

Top reporter: Acrotech Biopharma Inc

Corticosteroid [EPC]Alkylating Drug [EPC]Proteasome Inhibitor [EPC]Topoisomerase Inhibitor [EPC]Thalidomide Analog [EPC]

22,278

Total Reports

11,099

Serious Reports

5,109

Death Reports

Reported Reactions

Death Report Ratio: High (22.93%)

Patient Demographics

Male

9,713

Female

7,422

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Melphalan.

#	Reaction	Reports	% of Total
1	OFF LABEL USE	2,390	9.9%
2	DRUG INEFFECTIVE	1,356	5.6%
3	PLASMA CELL MYELOMA	1,258	5.2%
4	FEBRILE NEUTROPENIA	1,193	5.0%
5	NEUTROPENIA	1,114	4.6%
6	PYREXIA	1,051	4.4%
7	PNEUMONIA	1,047	4.4%
8	MUCOSAL INFLAMMATION	1,033	4.3%
9	THROMBOCYTOPENIA	1,028	4.3%
10	DIARRHOEA	969	4.0%
11	PRODUCT USE IN UNAPPROVED INDICATION	908	3.8%
12	SEPSIS	790	3.3%
13	DISEASE PROGRESSION	756	3.1%
14	INFECTION	692	2.9%
15	ANAEMIA	691	2.9%
16	NEUROPATHY PERIPHERAL	685	2.9%
17	MYELODYSPLASTIC SYNDROME	635	2.6%
18	DEATH	628	2.6%
19	PANCYTOPENIA	572	2.4%
20	ACUTE KIDNEY INJURY	553	2.3%
21	NAUSEA	544	2.3%
22	TOXICITY TO VARIOUS AGENTS	538	2.2%
23	VENOOCCLUSIVE LIVER DISEASE	512	2.1%
24	ACUTE GRAFT VERSUS HOST DISEASE	470	2.0%
25	ACUTE MYELOID LEUKAEMIA	456	1.9%
26	CYTOMEGALOVIRUS INFECTION	441	1.8%
27	GRAFT VERSUS HOST DISEASE	439	1.8%
28	VOMITING	436	1.8%
29	RENAL FAILURE	421	1.8%
30	THROMBOTIC MICROANGIOPATHY	421	1.8%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.