Methadone

Common brands: Methadone Hydrochloride, Methadose Sugar-Free, Methadose, Methadose Dispersible, Diskets

Top reporter: Vistapharm, Llc

Benzodiazepine [EPC]Opioid Agonist [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]Atypical Antipsychotic [EPC]Corticosteroid [EPC]
42,086
Total Reports
22,934
Serious Reports
13,531
Death Reports
30
Reported Reactions
Death Report Ratio: High (32.15%)

Patient Demographics

Male
20,809
Female
16,588

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Methadone.

# Reaction Reports % of Total
1 DRUG DEPENDENCE 5,634
9.9%
2 TOXICITY TO VARIOUS AGENTS 5,253
9.2%
3 DRUG ABUSE 4,851
8.5%
4 OVERDOSE 3,857
6.8%
5 PAIN 3,689
6.5%
6 DEATH 3,569
6.3%
7 EMOTIONAL DISTRESS 2,387
4.2%
8 DRUG WITHDRAWAL SYNDROME 2,353
4.1%
9 DRUG INEFFECTIVE 1,752
3.1%
10 FOETAL EXPOSURE DURING PREGNANCY 1,668
2.9%
11 NAUSEA 1,617
2.8%
12 DRUG INTERACTION 1,606
2.8%
13 ANXIETY 1,347
2.4%
14 DRUG WITHDRAWAL SYNDROME NEONATAL 1,347
2.4%
15 FATIGUE 1,314
2.3%
16 OFF LABEL USE 1,293
2.3%
17 VOMITING 1,266
2.2%
18 SOMNOLENCE 1,242
2.2%
19 COMPLETED SUICIDE 1,097
1.9%
20 CARDIAC ARREST 1,063
1.9%
21 DYSPNOEA 962
1.7%
22 DEPRESSION 945
1.7%
23 HEADACHE 943
1.7%
24 DEPENDENCE 898
1.6%
25 RESPIRATORY DEPRESSION 898
1.6%
26 PNEUMONIA 858
1.5%
27 ELECTROCARDIOGRAM QT PROLONGED 849
1.5%
28 INTENTIONAL PRODUCT MISUSE 842
1.5%
29 COMA 820
1.4%
30 DIARRHOEA 816
1.4%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.