Rifaximin

Common brands: Xifaxan, Generlac, Enulose, Constulose, Kristalose

Top reporter: Salix Pharmaceuticals, Inc.

Rifamycin Antibacterial [EPC]Osmotic Laxative [EPC]Loop Diuretic [EPC]Aldosterone Antagonist [EPC]Proton Pump Inhibitor [EPC]
20,331
Total Reports
11,330
Serious Reports
5,995
Death Reports
30
Reported Reactions
Death Report Ratio: High (29.49%)

Patient Demographics

Male
9,274
Female
10,159

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Rifaximin.

# Reaction Reports % of Total
1 DEATH 4,080
17.0%
2 HOSPITALISATION 1,763
7.4%
3 DIARRHOEA 1,218
5.1%
4 OFF LABEL USE 1,160
4.8%
5 THERAPY INTERRUPTED 1,057
4.4%
6 AMMONIA INCREASED 840
3.5%
7 NAUSEA 816
3.4%
8 FATIGUE 793
3.3%
9 HEPATIC ENCEPHALOPATHY 789
3.3%
10 DRUG INEFFECTIVE 728
3.0%
11 CONFUSIONAL STATE 719
3.0%
12 INABILITY TO AFFORD MEDICATION 688
2.9%
13 HEPATIC CIRRHOSIS 676
2.8%
14 INSURANCE ISSUE 661
2.8%
15 CONDITION AGGRAVATED 633
2.6%
16 FALL 615
2.6%
17 HEADACHE 531
2.2%
18 DIZZINESS 527
2.2%
19 PRODUCT USE IN UNAPPROVED INDICATION 527
2.2%
20 PRODUCT USE ISSUE 506
2.1%
21 HEPATIC FAILURE 487
2.0%
22 LIVER DISORDER 482
2.0%
23 ABDOMINAL PAIN 481
2.0%
24 VOMITING 480
2.0%
25 MALAISE 469
2.0%
26 PNEUMONIA 461
1.9%
27 DYSPNOEA 451
1.9%
28 ABDOMINAL DISTENSION 448
1.9%
29 ASTHENIA 446
1.9%
30 RENAL FAILURE 418
1.7%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.