Vincristine

Common brands: Cyclophosphamide, Frindovyx, Doxorubicin Hydrochloride, Methotrexate, Prednisone

Top reporter: Hospira, Inc.

Corticosteroid [EPC]Alkylating Drug [EPC]CD20-directed Cytolytic Antibody [EPC]Folate Analog Metabolic Inhibitor [EPC]Nucleoside Metabolic Inhibitor [EPC]
28,660
Total Reports
14,030
Serious Reports
5,333
Death Reports
30
Reported Reactions
Death Report Ratio: High (18.61%)

Patient Demographics

Male
12,993
Female
10,482

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Vincristine.

# Reaction Reports % of Total
1 FEBRILE NEUTROPENIA 4,315
14.7%
2 PYREXIA 1,874
6.4%
3 NEUTROPENIA 1,720
5.8%
4 OFF LABEL USE 1,690
5.7%
5 SEPSIS 1,084
3.7%
6 VOMITING 1,012
3.4%
7 DISEASE PROGRESSION 999
3.4%
8 NAUSEA 941
3.2%
9 PANCYTOPENIA 918
3.1%
10 PNEUMONIA 913
3.1%
11 HYPOTENSION 870
3.0%
12 THROMBOCYTOPENIA 834
2.8%
13 DEATH 824
2.8%
14 DRUG INEFFECTIVE 824
2.8%
15 ANAEMIA 806
2.7%
16 DIARRHOEA 759
2.6%
17 ABDOMINAL PAIN 749
2.5%
18 WHITE BLOOD CELL COUNT DECREASED 728
2.5%
19 MYELOSUPPRESSION 716
2.4%
20 PRODUCT USE IN UNAPPROVED INDICATION 692
2.4%
21 INTERSTITIAL LUNG DISEASE 680
2.3%
22 MUCOSAL INFLAMMATION 664
2.3%
23 SEPTIC SHOCK 659
2.2%
24 NEOPLASM PROGRESSION 649
2.2%
25 PLATELET COUNT DECREASED 645
2.2%
26 NEUROPATHY PERIPHERAL 633
2.2%
27 NEUTROPHIL COUNT DECREASED 588
2.0%
28 SECOND PRIMARY MALIGNANCY 567
1.9%
29 FATIGUE 545
1.9%
30 INFECTION 534
1.8%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.