Zidovudine

Common brands: Retrovir, Epivir, Lamivudine, Nevirapine, Norvir

Top reporter: Viiv Healthcare Company

Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]Protease Inhibitor [EPC]Cytochrome P450 3A Inhibitor [EPC]
13,223
Total Reports
3,231
Serious Reports
1,633
Death Reports
30
Reported Reactions
Death Report Ratio: High (12.35%)

Patient Demographics

Male
5,190
Female
4,221

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Zidovudine.

# Reaction Reports % of Total
1 FOETAL EXPOSURE DURING PREGNANCY 2,131
13.3%
2 DRUG EXPOSURE DURING PREGNANCY 1,075
6.7%
3 ANAEMIA 934
5.8%
4 VIROLOGIC FAILURE 814
5.1%
5 DRUG RESISTANCE 726
4.5%
6 PREMATURE BABY 723
4.5%
7 EXPOSURE DURING PREGNANCY 642
4.0%
8 PATHOGEN RESISTANCE 573
3.6%
9 VIRAL MUTATION IDENTIFIED 567
3.5%
10 MATERNAL EXPOSURE DURING PREGNANCY 508
3.2%
11 PYREXIA 469
2.9%
12 LIPODYSTROPHY ACQUIRED 435
2.7%
13 PAIN 427
2.7%
14 TREATMENT FAILURE 423
2.6%
15 NEUTROPENIA 414
2.6%
16 DEATH 411
2.6%
17 VOMITING 406
2.5%
18 ANXIETY 397
2.5%
19 DIARRHOEA 384
2.4%
20 EMOTIONAL DISTRESS 377
2.4%
21 DRUG INEFFECTIVE 359
2.2%
22 CAESAREAN SECTION 347
2.2%
23 DRUG INTERACTION 346
2.2%
24 ANHEDONIA 341
2.1%
25 IMMUNE RECONSTITUTION SYNDROME 303
1.9%
26 ALANINE AMINOTRANSFERASE INCREASED 296
1.9%
27 NAUSEA 296
1.9%
28 TREATMENT NONCOMPLIANCE 296
1.9%
29 HIV INFECTION 293
1.8%
30 ASPARTATE AMINOTRANSFERASE INCREASED 282
1.8%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.