Amphotericin B

Common brands: Ambisome, Vfend, Voriconazole, Vancomycin, Meropenem

Top reporter: Astellas Pharma Us, Inc.

Lipid-based Polyene Antifungal [EPC]Polyene Antifungal [EPC]Azole Antifungal [EPC]Corticosteroid [EPC]Glycopeptide Antibacterial [EPC]
17,945
Total Reports
11,341
Serious Reports
6,550
Death Reports
30
Reported Reactions
Death Report Ratio: High (36.50%)

Patient Demographics

Male
9,732
Female
6,592

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Amphotericin B.

# Reaction Reports % of Total
1 DRUG INEFFECTIVE 4,068
20.2%
2 OFF LABEL USE 1,983
9.8%
3 PYREXIA 984
4.9%
4 CONDITION AGGRAVATED 865
4.3%
5 FEBRILE NEUTROPENIA 656
3.3%
6 ACUTE KIDNEY INJURY 644
3.2%
7 SEPSIS 615
3.0%
8 PNEUMONIA 586
2.9%
9 HYPOKALAEMIA 554
2.7%
10 RENAL IMPAIRMENT 547
2.7%
11 MULTIPLE ORGAN DYSFUNCTION SYNDROME 538
2.7%
12 PRODUCT USE IN UNAPPROVED INDICATION 537
2.7%
13 DEATH 524
2.6%
14 NEUTROPENIA 518
2.6%
15 RESPIRATORY FAILURE 499
2.5%
16 SEPTIC SHOCK 490
2.4%
17 RENAL FAILURE 455
2.3%
18 DRUG INTERACTION 431
2.1%
19 ANAEMIA 421
2.1%
20 THROMBOCYTOPENIA 421
2.1%
21 NAUSEA 408
2.0%
22 BRONCHOPULMONARY ASPERGILLOSIS 406
2.0%
23 ASPERGILLUS INFECTION 403
2.0%
24 PANCYTOPENIA 398
2.0%
25 DIARRHOEA 392
1.9%
26 VOMITING 387
1.9%
27 DRUG INEFFECTIVE FOR UNAPPROVED INDICATION 382
1.9%
28 GENERAL PHYSICAL HEALTH DETERIORATION 366
1.8%
29 HYPOTENSION 355
1.8%
30 DYSPNOEA 345
1.7%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.