Brentuximab Vedotin

Common brands: Adcetris, Doxorubicin Hydrochloride, Dacarbazine, Cyclophosphamide, Frindovyx

Top reporter: Seagen Inc.

CD30-directed Immunoconjugate [EPC]Alkylating Drug [EPC]Corticosteroid [EPC]Topoisomerase Inhibitor [EPC]Platinum-based Drug [EPC]
9,949
Total Reports
5,955
Serious Reports
1,881
Death Reports
30
Reported Reactions
Death Report Ratio: High (18.91%)

Patient Demographics

Male
4,467
Female
3,253

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Brentuximab Vedotin.

# Reaction Reports % of Total
1 OFF LABEL USE 1,325
11.8%
2 FEBRILE NEUTROPENIA 725
6.4%
3 NEUROPATHY PERIPHERAL 686
6.1%
4 PYREXIA 676
6.0%
5 NEUTROPENIA 575
5.1%
6 DEATH 551
4.9%
7 HODGKIN^S DISEASE 450
4.0%
8 NAUSEA 384
3.4%
9 ANAEMIA 381
3.4%
10 DIARRHOEA 379
3.4%
11 THROMBOCYTOPENIA 373
3.3%
12 DRUG INEFFECTIVE 366
3.3%
13 DISEASE PROGRESSION 338
3.0%
14 PNEUMONIA 318
2.8%
15 WEIGHT DECREASED 317
2.8%
16 VOMITING 292
2.6%
17 RASH 266
2.4%
18 SEPSIS 257
2.3%
19 FATIGUE 251
2.2%
20 WHITE BLOOD CELL COUNT DECREASED 251
2.2%
21 MYELOSUPPRESSION 238
2.1%
22 DYSPNOEA 233
2.1%
23 ABDOMINAL PAIN 226
2.0%
24 MALIGNANT NEOPLASM PROGRESSION 223
2.0%
25 ASTHENIA 206
1.8%
26 POLYNEUROPATHY 198
1.8%
27 PRODUCT USE IN UNAPPROVED INDICATION 192
1.7%
28 HYPOTENSION 191
1.7%
29 NEUTROPHIL COUNT DECREASED 190
1.7%
30 ACUTE KIDNEY INJURY 184
1.6%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.