WEIGHT DECREASED

Adverse reaction reported in 595,573 FDA reports across 348 drugs.

595,573

Total Reports

348

Drugs Involved

Prednisone

Most Reported Drug

Drugs Associated with WEIGHT DECREASED

Drugs where "WEIGHT DECREASED" was reported as an adverse event.

#	Drug	Reports	% of Total
1	Prednisone	16,795	2.8%
2	Aspirin	13,257	2.2%
3	Acetaminophen	12,558	2.1%
4	Ergocalciferol	12,355	2.1%
5	Metformin	12,130	2.0%
6	Exenatide	12,124	2.0%
7	Levothyroxine	9,907	1.7%
8	Furosemide	9,771	1.6%
9	Gabapentin	8,583	1.4%
10	Omeprazole	8,204	1.4%
11	Pantoprazole	8,096	1.4%
12	Lisinopril	8,019	1.3%
13	Atorvastatin	6,847	1.1%
14	Metoprolol	6,533	1.1%
15	Insulin Glargine	6,364	1.1%
16	Amlodipine	6,066	1.0%
17	Simvastatin	5,841	1.0%
18	Acetaminophen, Guaifenesin, / Phenylephrine Hydrochloride	5,518	0.9%
19	Calcium	5,422	0.9%
20	Alprazolam	5,408	0.9%
21	Rosuvastatin	5,301	0.9%
22	Sacubitril / Valsartan	5,191	0.9%
23	Lorazepam	5,179	0.9%
24	Apremilast	4,992	0.8%
25	Clonazepam	4,716	0.8%
26	Losartan	4,637	0.8%
27	Hydrochlorothiazide	4,318	0.7%
28	Semaglutide	4,038	0.7%
29	Clopidogrel	3,950	0.7%
30	Methylprednisolone	3,874	0.7%
31	Hydrocortisone	3,865	0.6%
32	Spironolactone	3,736	0.6%
33	Treprostinil	3,727	0.6%
34	Chloride	3,568	0.6%
35	Carvedilol	3,469	0.6%
36	Omalizumab	3,448	0.6%
37	Atenolol	3,440	0.6%
38	Dulaglutide	3,390	0.6%
39	Azathioprine	3,332	0.6%
40	Vitamin C	3,318	0.6%
41	Escitalopram	3,284	0.6%
42	Citalopram	3,186	0.5%
43	Allopurinol	3,111	0.5%
44	Vedolizumab	3,105	0.5%
45	Tiotropium Bromide	3,089	0.5%
46	Zolpidem	3,049	0.5%
47	Magnesium	3,046	0.5%
48	Cabozantinib	3,002	0.5%
49	Topiramate	2,999	0.5%
50	Insulin Lispro	2,989	0.5%
51	Nintedanib	2,913	0.5%
52	Chloride Extended-	2,890	0.5%
53	Potassium Chloride, Dextrose Monohydrate	2,889	0.5%
54	Oxybate	2,883	0.5%
55	Valsartan	2,861	0.5%
56	Budesonide / Formoterol Fumarate Dihydrate	2,847	0.5%
57	Empagliflozin	2,841	0.5%
58	Warfarin	2,837	0.5%
59	Glipizide	2,825	0.5%
60	Infliximab-Dyyb	2,819	0.5%
61	Ondansetron	2,726	0.5%
62	Mesalamine	2,689	0.5%
63	Peginterferon Alfa-2a	2,659	0.4%
64	Mycophenolate	2,658	0.4%
65	Famotidine	2,637	0.4%
66	Denosumab	2,592	0.4%
67	Ribavirin	2,587	0.4%
68	Hydrocortisone 1%	2,583	0.4%
69	Anti Itch	2,581	0.4%
70	Anti-Itch	2,581	0.4%
71	Anti-Pruritic	2,581	0.4%
72	Antipruritic (Anti-Itch)	2,581	0.4%
73	Cool Relief With Aloe	2,581	0.4%
74	Drs Hydrocortisone	2,581	0.4%
75	Hydrocortisone Continuous Spray	2,581	0.4%
76	Hydrocortisone Spray	2,581	0.4%
77	Fish Oil	2,579	0.4%
78	Diphenhydramine	2,507	0.4%
79	Iron	2,493	0.4%
80	Morphine	2,383	0.4%
81	Fluticasone	2,334	0.4%
82	Octreotide	2,264	0.4%
83	Tadalafil	2,232	0.4%
84	Teriparatide	2,225	0.4%
85	Pirfenidone	2,214	0.4%
86	Olmesartan Medoxomil	2,205	0.4%
87	Mirtazapine	2,203	0.4%
88	Sulfamethoxazole / Trimethoprim	2,171	0.4%
89	Tirzepatide	2,122	0.4%
90	Liraglutide	2,107	0.4%
91	Polyethylene Glycol 3350	2,102	0.4%
92	Pioglitazone	2,087	0.4%
93	Fluticasone Propionate / Salmeterol Xinafoate	2,078	0.3%
94	Digoxin	2,071	0.3%
95	Loperamide	2,060	0.3%
96	Budesonide	2,032	0.3%
97	Capecitabine	2,022	0.3%
98	Loratadine	1,988	0.3%
99	Oxygen	1,983	0.3%
100	0xygen	1,983	0.3%
101	Palbociclib	1,969	0.3%
102	Everolimus	1,926	0.3%
103	Antacid	1,922	0.3%
104	Sitagliptin	1,921	0.3%
105	Dapagliflozin	1,903	0.3%
106	Insulin Aspart	1,861	0.3%
107	Montelukast	1,857	0.3%
108	Hydromorphone	1,830	0.3%
109	Nivolumab	1,819	0.3%
110	Ezetimibe	1,806	0.3%
111	Docusate	1,806	0.3%
112	Fentanyl	1,792	0.3%
113	Metronidazole	1,787	0.3%
114	Enzalutamide	1,779	0.3%
115	Pembrolizumab	1,774	0.3%
116	Insulin	1,719	0.3%
117	Pancrelipase	1,709	0.3%
118	Metoroprolol	1,676	0.3%
119	Epinephrine	1,646	0.3%
120	Meloxicam	1,639	0.3%
121	Escitalopram Oxalate	1,621	0.3%
122	Amoxicillin	1,609	0.3%
123	Sunitinib Malate	1,588	0.3%
124	Sildenafil	1,563	0.3%
125	Esomeprazole	1,544	0.3%
126	Glyburide	1,540	0.3%
127	Loperamide Hydrochloride / Dimethicone	1,502	0.3%
128	Melatonin	1,496	0.3%
129	Nitroglycerin	1,479	0.2%
130	Topiramate Spinkle	1,427	0.2%
131	Ferrous	1,419	0.2%
132	Lenvatinib	1,403	0.2%
133	Glimepiride	1,401	0.2%
134	Vitamin E	1,401	0.2%
135	Carbidopa / Levodopa	1,400	0.2%
136	Diltiazem	1,353	0.2%
137	Canagliflozin	1,341	0.2%
138	Insulin Human	1,317	0.2%
139	Multivitamin	1,283	0.2%
140	Clonidine	1,263	0.2%
141	Finasteride	1,242	0.2%
142	Teduglutide	1,242	0.2%
143	Adrenalinum	1,227	0.2%
144	Enalapril	1,226	0.2%
145	Irbesartan	1,209	0.2%
146	Cyanocobalamin	1,189	0.2%
147	Temazepam	1,184	0.2%
148	Riociguat	1,167	0.2%
149	Lidocaine Hydrochloride / Epinephrine Bitartrate	1,163	0.2%
150	Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate / Amphetamine Aspartate	1,160	0.2%
151	Leuprolide	1,157	0.2%
152	Azithromycin	1,157	0.2%
153	Ipratropium Bromide	1,138	0.2%
154	Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	1,114	0.2%
155	Modafinil	1,102	0.2%
156	Lidocaine, Menthol	1,100	0.2%
157	Burn Relief	1,097	0.2%
158	Lidicaine	1,097	0.2%
159	Nifedipine	1,093	0.2%
160	Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol / Niacinamide	1,085	0.2%
161	Oxide	1,083	0.2%
162	Divalproex	1,063	0.2%
163	Teriflunomide	1,060	0.2%
164	Selexipag	1,034	0.2%
165	Fulvestrant	1,029	0.2%
166	Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, / Amphetamine Sulfate	1,018	0.2%
167	Sucralfate	1,011	0.2%
168	Insulin Detemir	978	0.2%
169	Lactulose	972	0.2%
170	Latanoprost	955	0.2%
171	Lisdexamfetamine Dimesylate	950	0.2%
172	Fenofibrate	949	0.2%
173	Torsemide	934	0.2%
174	Sorafenib	917	0.2%
175	Biotin	895	0.2%
176	Pazopanib	882	0.1%
177	Dexlansoprazole	879	0.1%
178	Diphenoxylate Hydrochloride / Atropine Sulfate	868	0.1%
179	Human Immunoglobulin G	857	0.1%
180	Cannabidiol	849	0.1%
181	Zinc Chloride	846	0.1%
182	Zinc Gluconate	845	0.1%
183	Ciclesonide	833	0.1%
184	Rabeprazole	809	0.1%
185	Zinc	802	0.1%
186	Axitinib	798	0.1%
187	Prochlorperazine	788	0.1%
188	Donepezil	784	0.1%
189	Clarithromycin	766	0.1%
190	Guaifenesin	765	0.1%
191	Testosterone	752	0.1%
192	Sennosides	751	0.1%
193	Nystatin	750	0.1%
194	Armodafinil	743	0.1%
195	Atomoxetine	736	0.1%
196	Exemestane	735	0.1%
197	Vismodegib	732	0.1%
198	Dimenhydrinate	720	0.1%
199	Sitagliptin / Metformin Hydrochloride	709	0.1%
200	Lovastatin	695	0.1%
201	Promethazine	693	0.1%
202	Epoprostenol	685	0.1%
203	Cetuximab	674	0.1%
204	Candesartan Cilexetil	670	0.1%
205	Bumetanide	663	0.1%
206	Ticagrelor	658	0.1%
207	Ipilimumab	653	0.1%
208	Selinexor	637	0.1%
209	Regorafenib	633	0.1%
210	Ibuprofen / Diphenhydramine Citrate	629	0.1%
211	Methocarbamol	622	0.1%
212	Ciprofloxacin Hydrochloride / Hydrocortisone	609	0.1%
213	Bicarbonate	606	0.1%
214	Carisoprodol	595	0.1%
215	Nitrofurantoin (Monohydrate / Macrocrystals)	594	0.1%
216	Nitrofurantoin Monohydrate / Macrocrystals	594	0.1%
217	Nitrofurantoin	588	0.1%
218	Oxybutynin	585	0.1%
219	Rivastigmine	582	0.1%
220	Clindamycin	581	0.1%
221	Amoxicillin / Clavulanate Potassium	570	0.1%
222	Senna Leaf	565	0.1%
223	Deferasirox	564	0.1%
224	Mupirocin	555	0.1%
225	Desvenlafaxine	553	0.1%
226	Pertuzumab	546	0.1%
227	Senna	544	0.1%
228	Erythropoietin	539	0.1%
229	Erythromycin	534	0.1%
230	Bisacodyl	529	0.1%
231	Naproxen Sodium, Pseudoephedrine Hydrochloride	522	0.1%
232	Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	522	0.1%
233	Alpelisib	520	0.1%
234	Dicyclomine	518	0.1%
235	Extended Phenytoin	511	0.1%
236	Ezetimibe / Simvastatin	502	0.1%
237	Cholestyramine	502	0.1%
238	Linaclotide	501	0.1%
239	Calcitriol	500	0.1%
240	Insulin Degludec	498	0.1%
241	Tamsulosin	497	0.1%
242	Biscodyl	489	0.1%
243	Bisacodyl Suppositories	487	0.1%
244	Tolterodine	486	0.1%
245	Pravastatin	479	0.1%
246	Clotrimazole	479	0.1%
247	Meclizine	478	0.1%
248	Insulin Glargine-Yfgn	477	0.1%
249	Osimertinib	469	0.1%
250	Abemaciclib	469	0.1%
251	Fluticasone Furoate	462	0.1%
252	Drs Clotrimazole	455	0.1%
253	Family Wellness Clotrimazole	455	0.1%
254	Clobazam	448	0.1%
255	Tobramycin	440	0.1%
256	Gemfibrozil	428	0.1%
257	Ursodiol	425	0.1%
258	Eszopiclone	424	0.1%
259	Benzonatate	424	0.1%
260	Ropinirole	415	0.1%
261	Dronabinol	415	0.1%
262	Amikacin	414	0.1%
263	Ziprasidone	413	0.1%
264	Indapamide	406	0.1%
265	Psyllium Husk	404	0.1%
266	Ursosiol	401	0.1%
267	Amantadine	401	0.1%
268	And Oxybates	396	0.1%
269	Ketoconazole	389	0.1%
270	Carboxymethylcellulose	379	0.1%
271	Bicalutamide	374	0.1%
272	Lanreotide	374	0.1%
273	Zonisamide	371	0.1%
274	Lapatinib	369	0.1%
275	Trazodone	369	0.1%
276	Human Insulin	366	0.1%
277	Sotalol	365	0.1%
278	Nicotine Polacrilex Mini	365	0.1%
279	Nicotine Polarilex	365	0.1%
280	Oxybutynin Chloride	360	0.1%
281	Valsartan / Hydrochlorothiazide	353	0.1%
282	Metolazone	350	0.1%
283	Hyoscyamine	350	0.1%
284	Palivizumab	342	0.1%
285	Theophylline	340	0.1%
286	Omega-3-Acid Ethyl Esters	337	0.1%
287	Niacin	337	0.1%
288	Polyethylene Glycol 400	335	0.1%
289	Chlorthalidone	332	0.1%
290	Primidone	331	0.1%
291	Instalax Polyethylene Glycol 3350	330	0.1%
292	Polyethylene Glycol (3350)	330	0.1%
293	Isoniazid	329	0.1%
294	Trifluridine / Tipiracil	329	0.1%
295	Agalsidase Beta	328	0.1%
296	Dornase Alfa	321	0.1%
297	Butalbital, Acetaminophen, / Caffeine	320	0.1%
298	Ketoconazole Foam	317	0.1%
299	Brentuximab Vedotin	317	0.1%
300	Ado-Trastuzumab Emtansine	316	0.1%
301	Losartan Potassium / Hydrochlorothiazide	314	0.1%
302	Doxepin	313	0.1%
303	Rasagiline	302	0.1%
304	Rotigotine	300	0.1%
305	Buspirone	300	0.1%
306	Thyroid, Porcine	299	0.1%
307	Fesoterodine	297	0.0%
308	Rucaparib	296	0.0%
309	Colesevelam	295	0.0%
310	Liothyronine	291	0.0%
311	Tafamidis	289	0.0%
312	Rizatriptan Benzoate	275	0.0%
313	Amlodipine Besylate / Benazepril Hydrochloride	273	0.0%
314	Eplerenone	268	0.0%
315	Memantine	262	0.0%
316	Goserelin	258	0.0%
317	Lisinopril / Hydrochlorothiazide	257	0.0%
318	Lubiprostone	257	0.0%
319	Quinapril	253	0.0%
320	Voxelotor	251	0.0%
321	Rifampin	247	0.0%
322	Labetalol	242	0.0%
323	Polyethylene Glycol	241	0.0%
324	Lidocaine Patch 5%	239	0.0%
325	Apalutamide	236	0.0%
326	Erlotinib	236	0.0%
327	Terazosin	234	0.0%
328	Fam-Trastuzumab Deruxtecan-Nxki	233	0.0%
329	Desloratadine	232	0.0%
330	Terbinafine	220	0.0%
331	Bosutinib	218	0.0%
332	Vemurafenib	215	0.0%
333	Asfotase Alfa	214	0.0%
334	Insulin Glulisine	210	0.0%
335	Quinine	209	0.0%
336	Dofetilide	200	0.0%
337	Clobetasol	198	0.0%
338	Clobetasol Propionate Ointment Usp, 0.05%	198	0.0%
339	Salmeterol	198	0.0%
340	Crizotinib	194	0.0%
341	Dronedarone	179	0.0%
342	Vilazodone	170	0.0%
343	Gefitinib	153	0.0%
344	Lumacaftor / Ivacaftor	147	0.0%
345	Cladribine	135	0.0%
346	Emicizumab	132	0.0%
347	Ivacaftor	102	0.0%
348	Lutetium Lu 177 Vipivotide Tetraxetan	61	0.0%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. The presence of a drug in this list does not mean the drug caused weight decreased. Always consult your healthcare provider.