Buprenorphine Hydrochloride, Naloxone Hydrochloride
Common brands: Suboxone, Oxycontin, Hydrocodone Bitartrate And Acetaminophen, Neurontin, Oxycodone Hydrochloride
Top reporter: Indivior Inc.
Benzodiazepine [EPC]Partial Opioid Agonist [EPC]Opioid Agonist [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]Atypical Antipsychotic [EPC]
23,840
Total Reports
5,920
Serious Reports
1,254
Death Reports
30
Reported Reactions
Death Report Ratio: High (5.26%)
Patient Demographics
Reported Adverse Reactions (30)
Side effects reported in FDA adverse event reports for Buprenorphine Hydrochloride, Naloxone Hydrochloride.
| # | Reaction | Reports | % of Total |
|---|---|---|---|
| 1 | DRUG DEPENDENCE | 4,290 | |
| 2 | DRUG WITHDRAWAL SYNDROME | 3,338 | |
| 3 | PAIN | 2,558 | |
| 4 | OFF LABEL USE | 2,071 | |
| 5 | OVERDOSE | 1,858 | |
| 6 | NAUSEA | 1,639 | |
| 7 | EMOTIONAL DISTRESS | 1,478 | |
| 8 | ANXIETY | 1,353 | |
| 9 | VOMITING | 1,341 | |
| 10 | HEADACHE | 1,114 | |
| 11 | DRUG ABUSE | 1,104 | |
| 12 | INSOMNIA | 1,076 | |
| 13 | FOETAL EXPOSURE DURING PREGNANCY | 1,049 | |
| 14 | DEPRESSION | 1,030 | |
| 15 | INTENTIONAL UNDERDOSE | 1,026 | |
| 16 | FEELING ABNORMAL | 1,014 | |
| 17 | SUBSTANCE ABUSE | 1,006 | |
| 18 | PRODUCT USE ISSUE | 978 | |
| 19 | DRUG WITHDRAWAL SYNDROME NEONATAL | 908 | |
| 20 | WRONG TECHNIQUE IN PRODUCT USAGE PROCESS | 805 | |
| 21 | INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION | 784 | |
| 22 | FATIGUE | 775 | |
| 23 | PRODUCT PREPARATION ERROR | 775 | |
| 24 | MATERNAL EXPOSURE DURING PREGNANCY | 736 | |
| 25 | MALAISE | 726 | |
| 26 | HYPERHIDROSIS | 716 | |
| 27 | WRONG TECHNIQUE IN DRUG USAGE PROCESS | 662 | |
| 28 | DENTAL CARIES | 652 | |
| 29 | DRUG INEFFECTIVE | 648 | |
| 30 | DIARRHOEA | 631 |
Important Disclaimer
FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.