Carbidopa / Levodopa

Common brands: Sinemet, Rytary, Duopa, Nuplazid, Carbidopa-Levodopa

Top reporter: Amneal Pharmaceuticals Llc

Aromatic Amino Acid [EPC]Aromatic Amino Acid Decarboxylation Inhibitor [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]Benzodiazepine [EPC]Platelet Aggregation Inhibitor [EPC]
46,490
Total Reports
19,014
Serious Reports
5,810
Death Reports
30
Reported Reactions
Death Report Ratio: High (12.50%)

Patient Demographics

Male
24,707
Female
18,966

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Carbidopa / Levodopa.

# Reaction Reports % of Total
1 FALL 4,375
7.5%
2 DRUG INEFFECTIVE 4,032
6.9%
3 HALLUCINATION 3,837
6.6%
4 TREMOR 3,281
5.6%
5 DYSKINESIA 2,954
5.1%
6 DEATH 2,816
4.8%
7 PARKINSON^S DISEASE 2,500
4.3%
8 DIZZINESS 2,481
4.3%
9 NAUSEA 2,343
4.0%
10 CONFUSIONAL STATE 2,121
3.6%
11 GAIT DISTURBANCE 2,000
3.4%
12 FATIGUE 1,978
3.4%
13 SOMNOLENCE 1,966
3.4%
14 ASTHENIA 1,819
3.1%
15 URINARY TRACT INFECTION 1,457
2.5%
16 WEIGHT DECREASED 1,400
2.4%
17 ANXIETY 1,395
2.4%
18 MALAISE 1,392
2.4%
19 INSOMNIA 1,361
2.3%
20 CONSTIPATION 1,353
2.3%
21 DEVICE ISSUE 1,287
2.2%
22 CONDITION AGGRAVATED 1,274
2.2%
23 FEELING ABNORMAL 1,264
2.2%
24 DYSPNOEA 1,238
2.1%
25 BALANCE DISORDER 1,135
2.0%
26 COUGH 1,095
1.9%
27 HYPOTENSION 1,017
1.7%
28 ON AND OFF PHENOMENON 1,010
1.7%
29 PAIN 999
1.7%
30 DEVICE DISLOCATION 976
1.7%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.