CONSTIPATION

Adverse reaction reported in 297,014 FDA reports across 209 drugs.

297,014

Total Reports

209

Drugs Involved

Aspirin

Most Reported Drug

Drugs Associated with CONSTIPATION

Drugs where "CONSTIPATION" was reported as an adverse event.

#	Drug	Reports	% of Total
1	Aspirin	11,417	3.8%
2	Lenalidomide	10,965	3.7%
3	Ergocalciferol	10,048	3.4%
4	Gabapentin	7,922	2.7%
5	Levothyroxine	7,707	2.6%
6	Omeprazole	7,450	2.5%
7	Dexamethasone	6,798	2.3%
8	Tirzepatide	5,248	1.8%
9	Polyethylene Glycol 3350	5,218	1.8%
10	Semaglutide	4,668	1.6%
11	Rosuvastatin	4,480	1.5%
12	Alprazolam	4,437	1.5%
13	Niraparib	4,103	1.4%
14	Ondansetron	4,006	1.3%
15	Losartan	3,735	1.3%
16	Docusate	3,460	1.2%
17	Allopurinol	3,191	1.1%
18	Erenumab-Aooe	3,179	1.1%
19	Chloride	3,012	1.0%
20	Albuterol	2,941	1.0%
21	Acyclovir	2,882	1.0%
22	Famotidine	2,826	1.0%
23	Palbociclib	2,779	0.9%
24	Pomalidomide	2,629	0.9%
25	Magnesium	2,606	0.9%
26	Sevelamer Carbonate	2,541	0.9%
27	Teriparatide	2,538	0.9%
28	Lactulose	2,527	0.9%
29	Chloride Extended-	2,520	0.8%
30	Potassium Chloride, Dextrose Monohydrate	2,519	0.8%
31	Loperamide	2,407	0.8%
32	Cabozantinib	2,352	0.8%
33	Clozapine	2,344	0.8%
34	Bevacizumab	2,280	0.8%
35	Morphine	2,270	0.8%
36	Dulaglutide	2,246	0.8%
37	Varenicline	2,209	0.7%
38	Bortezomib	2,181	0.7%
39	Vedolizumab	2,180	0.7%
40	Patiromer	2,141	0.7%
41	Hydromorphone	2,122	0.7%
42	Cyclobenzaprine	2,120	0.7%
43	Orlistat	1,991	0.7%
44	Nintedanib	1,973	0.7%
45	Fentanyl	1,959	0.7%
46	Linaclotide	1,937	0.7%
47	Sennosides	1,910	0.6%
48	Capecitabine	1,880	0.6%
49	Iron	1,849	0.6%
50	Melatonin	1,846	0.6%
51	Nitroglycerin	1,843	0.6%
52	Enzalutamide	1,817	0.6%
53	Loperamide Hydrochloride / Dimethicone	1,738	0.6%
54	Letrozole	1,666	0.6%
55	Fluconazole	1,649	0.6%
56	Solifenacin	1,622	0.5%
57	Hydroxide	1,615	0.5%
58	Liraglutide	1,570	0.5%
59	Duloxetine	1,547	0.5%
60	Bisacodyl	1,534	0.5%
61	Senna Leaf	1,494	0.5%
62	Sitagliptin	1,475	0.5%
63	Oxide	1,433	0.5%
64	Biscodyl	1,425	0.5%
65	Metronidazole	1,416	0.5%
66	Bisacodyl Suppositories	1,413	0.5%
67	Metoroprolol	1,380	0.5%
68	Carbamazepine	1,379	0.5%
69	Nivolumab	1,372	0.5%
70	Glipizide	1,359	0.5%
71	Clonidine	1,353	0.5%
72	Carbidopa / Levodopa	1,353	0.5%
73	Pimavanserin	1,336	0.4%
74	Standardized Senna	1,330	0.4%
75	Temazepam	1,315	0.4%
76	Mirabegron	1,312	0.4%
77	Olmesartan Medoxomil	1,300	0.4%
78	Insulin Aspart	1,291	0.4%
79	Levofloxacin	1,263	0.4%
80	Levofloxacin In 5% Dextrose	1,263	0.4%
81	Finasteride	1,216	0.4%
82	Ferrous	1,204	0.4%
83	Exenatide	1,177	0.4%
84	Senna	1,177	0.4%
85	Diltiazem	1,143	0.4%
86	Zinc Gluconate	1,124	0.4%
87	Zinc Chloride	1,113	0.4%
88	Ribociclib	1,091	0.4%
89	Vitamin E	1,080	0.4%
90	Zinc	1,080	0.4%
91	Multivitamin	1,048	0.4%
92	Sunitinib Malate	1,010	0.3%
93	Thalidomide	995	0.3%
94	Biotin	993	0.3%
95	Relugolix	988	0.3%
96	Ixazomib	963	0.3%
97	Pancrelipase	958	0.3%
98	Ipratropium Bromide	955	0.3%
99	Prochlorperazine	940	0.3%
100	Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol / Niacinamide	879	0.3%
101	Psyllium Husk	874	0.3%
102	Sucralfate	870	0.3%
103	Lenvatinib	867	0.3%
104	Oxazepam	861	0.3%
105	Glimepiride	853	0.3%
106	Ascorbic Acid	851	0.3%
107	Valacyclovir	800	0.3%
108	Pirfenidone	790	0.3%
109	Rucaparib	783	0.3%
110	Amitriptyline	778	0.3%
111	Progesterone	738	0.2%
112	Darbepoetin Alfa	737	0.2%
113	Oxybutynin	735	0.2%
114	Calcitriol	712	0.2%
115	Quinapril	711	0.2%
116	Bicarbonate	706	0.2%
117	Polyethylene Glycol 400	690	0.2%
118	Instalax Polyethylene Glycol 3350	682	0.2%
119	Polyethylene Glycol (3350)	682	0.2%
120	Insulin Degludec	663	0.2%
121	Daratumumab	659	0.2%
122	Galcanezumab-Gnlm	655	0.2%
123	Guaifenesin	648	0.2%
124	Naltrexone Hydrochloride / Bupropion Hydrochloride	646	0.2%
125	Abemaciclib	635	0.2%
126	Ketoprofen	632	0.2%
127	Atezolizumab	628	0.2%
128	Tolterodine	617	0.2%
129	Rabeprazole	614	0.2%
130	Lubiprostone	573	0.2%
131	Azacitidine	554	0.2%
132	Pertuzumab	552	0.2%
133	Lovastatin	547	0.2%
134	Amantadine	537	0.2%
135	Dasatinib	528	0.2%
136	Axitinib	520	0.2%
137	Promethazine	511	0.2%
138	Sorafenib	509	0.2%
139	Dicyclomine	504	0.2%
140	Fesoterodine	504	0.2%
141	Diphenoxylate Hydrochloride / Atropine Sulfate	498	0.2%
142	Pramipexole	472	0.2%
143	Temozolomide	461	0.2%
144	Crizotinib	438	0.1%
145	Selinexor	436	0.1%
146	Polyethylene Glycol	434	0.1%
147	Benzonatate	433	0.1%
148	Meclizine	431	0.1%
149	Dalteparin	425	0.1%
150	Regorafenib	422	0.1%
151	Trazodone	417	0.1%
152	Phytonadione	413	0.1%
153	Vortioxetine	409	0.1%
154	Olaparib	408	0.1%
155	Nicotine Polacrilex Mini	407	0.1%
156	Nicotine Polarilex	407	0.1%
157	Oxybutynin Chloride	400	0.1%
158	Cholestyramine	398	0.1%
159	Ursodiol	396	0.1%
160	Rasagiline	395	0.1%
161	Colesevelam	395	0.1%
162	Pravastatin	393	0.1%
163	Granisetron	393	0.1%
164	Cinacalcet	392	0.1%
165	Clotrimazole	390	0.1%
166	Mupirocin	388	0.1%
167	Fluticasone Furoate	385	0.1%
168	Vismodegib	378	0.1%
169	Bicalutamide	374	0.1%
170	Dextrose	374	0.1%
171	Eszopiclone	369	0.1%
172	Ursosiol	365	0.1%
173	Drs Clotrimazole	364	0.1%
174	Family Wellness Clotrimazole	364	0.1%
175	Trametinib	360	0.1%
176	Heparin	359	0.1%
177	Cannabidiol	336	0.1%
178	Trifluridine / Tipiracil	327	0.1%
179	Tapentadol	326	0.1%
180	Ledipasvir / Sofosbuvir	325	0.1%
181	Fremanezumab-Vfrm	296	0.1%
182	Carboxymethylcellulose	294	0.1%
183	Lanreotide	291	0.1%
184	Niacin	281	0.1%
185	Chlorthalidone	278	0.1%
186	Hyoscyamine	275	0.1%
187	Elexacaftor, Tezacaftor, / Ivacaftor	271	0.1%
188	Ado-Trastuzumab Emtansine	268	0.1%
189	Abiraterone	258	0.1%
190	Memantine	255	0.1%
191	Quinine	254	0.1%
192	Lidocaine Patch 5%	251	0.1%
193	Terazosin	245	0.1%
194	Atropine	238	0.1%
195	Thyroid, Porcine	235	0.1%
196	Lisinopril / Hydrochlorothiazide	233	0.1%
197	Oseltamivir	231	0.1%
198	Primidone	228	0.1%
199	Dronabinol	219	0.1%
200	Fam-Trastuzumab Deruxtecan-Nxki	216	0.1%
201	Encorafenib	212	0.1%
202	Bosutinib	207	0.1%
203	Rimegepant	195	0.1%
204	Erlotinib	179	0.1%
205	Timolol	178	0.1%
206	Velpatasvir / Sofosbuvir	173	0.1%
207	Apalutamide	148	0.0%
208	Glecaprevir / Pibrentasvir	139	0.0%
209	Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	107	0.0%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. The presence of a drug in this list does not mean the drug caused constipation. Always consult your healthcare provider.