Clozapine

Common brands: Clozaril, Versacloz, Zyprexa Zydis, Zyprexa Intramuscular, Zyprexa

Top reporter: Hls Therapeutics (Usa), Inc.

Atypical Antipsychotic [EPC]Benzodiazepine [EPC]Anti-epileptic Agent [EPC]Mood Stabilizer [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]
123,199
Total Reports
63,195
Serious Reports
21,916
Death Reports
30
Reported Reactions
Death Report Ratio: High (17.79%)

Patient Demographics

Male
66,570
Female
42,460

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Clozapine.

# Reaction Reports % of Total
1 NEUTROPENIA 18,816
15.2%
2 HOSPITALISATION 12,262
9.9%
3 DEATH 11,746
9.5%
4 SCHIZOPHRENIA 4,610
3.7%
5 WHITE BLOOD CELL COUNT INCREASED 4,478
3.6%
6 WHITE BLOOD CELL COUNT DECREASED 4,432
3.6%
7 NEUTROPHIL COUNT INCREASED 4,147
3.3%
8 DRUG INEFFECTIVE 3,910
3.2%
9 MALAISE 3,773
3.0%
10 OFF LABEL USE 3,685
3.0%
11 PNEUMONIA 3,227
2.6%
12 TREATMENT NONCOMPLIANCE 3,181
2.6%
13 NEUTROPHIL COUNT DECREASED 3,139
2.5%
14 DRUG INTERACTION 3,095
2.5%
15 HAEMOGLOBIN DECREASED 3,085
2.5%
16 PSYCHOTIC DISORDER 3,083
2.5%
17 TACHYCARDIA 2,808
2.3%
18 FALL 2,680
2.2%
19 LEUKOPENIA 2,619
2.1%
20 GRANULOCYTOPENIA 2,616
2.1%
21 PYREXIA 2,576
2.1%
22 NEUTROPHILIA 2,561
2.1%
23 CONSTIPATION 2,344
1.9%
24 SEDATION 2,278
1.8%
25 MENTAL IMPAIRMENT 2,250
1.8%
26 SOMNOLENCE 2,241
1.8%
27 MYOCARDITIS 2,172
1.8%
28 AGRANULOCYTOSIS 2,065
1.7%
29 VOMITING 2,026
1.6%
30 CONFUSIONAL STATE 1,945
1.6%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.