Fam-Trastuzumab Deruxtecan-Nxki

Common brands: Enhertu, Herceptin, Xeloda, Perjeta, Ontruzant

Top reporter: Daiichi Sankyo Inc.

HER2/neu Receptor Antagonist [EPC]Corticosteroid [EPC]Nucleoside Metabolic Inhibitor [EPC]Kinase Inhibitor [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]
9,187
Total Reports
8,481
Serious Reports
2,340
Death Reports
30
Reported Reactions
Death Report Ratio: High (25.47%)

Patient Demographics

Male
1,001
Female
7,079

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Fam-Trastuzumab Deruxtecan-Nxki.

# Reaction Reports % of Total
1 NAUSEA 1,137
9.5%
2 DEATH 1,064
8.9%
3 INTERSTITIAL LUNG DISEASE 982
8.2%
4 DISEASE PROGRESSION 968
8.1%
5 OFF LABEL USE 763
6.4%
6 FATIGUE 730
6.1%
7 DIARRHOEA 533
4.5%
8 VOMITING 516
4.3%
9 PNEUMONITIS 369
3.1%
10 DECREASED APPETITE 354
3.0%
11 NO ADVERSE EVENT 349
2.9%
12 ASTHENIA 334
2.8%
13 ALOPECIA 325
2.7%
14 DYSPNOEA 299
2.5%
15 INTENTIONAL PRODUCT USE ISSUE 248
2.1%
16 NEUTROPENIA 240
2.0%
17 METASTASES TO CENTRAL NERVOUS SYSTEM 238
2.0%
18 WEIGHT DECREASED 233
2.0%
19 MALAISE 232
1.9%
20 PNEUMONIA 226
1.9%
21 CONSTIPATION 216
1.8%
22 MYELOSUPPRESSION 206
1.7%
23 ANAEMIA 199
1.7%
24 DRUG INEFFECTIVE 185
1.6%
25 PLATELET COUNT DECREASED 179
1.5%
26 NEUTROPHIL COUNT DECREASED 174
1.5%
27 PYREXIA 172
1.4%
28 MALIGNANT NEOPLASM PROGRESSION 160
1.3%
29 ASCITES 153
1.3%
30 THROMBOCYTOPENIA 149
1.2%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.