Orlistat

Common brands: Alli, Xenical, Ecotrin, Aspirin 325, Aspirin 81

Top reporter: Haleon Us Holdings Llc

Intestinal Lipase Inhibitor [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]Proton Pump Inhibitor [EPC]HMG-CoA Reductase Inhibitor [EPC]Platelet Aggregation Inhibitor [EPC]
25,681
Total Reports
1,558
Serious Reports
230
Death Reports
30
Reported Reactions
Death Report Ratio: Low (0.90%)

Patient Demographics

Male
2,389
Female
16,105

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Orlistat.

# Reaction Reports % of Total
1 DRUG INEFFECTIVE 4,525
14.1%
2 RECTAL DISCHARGE 2,432
7.6%
3 GASTROINTESTINAL DISORDER 2,185
6.8%
4 CONSTIPATION 1,991
6.2%
5 DIARRHOEA 1,952
6.1%
6 WEIGHT INCREASED 1,944
6.0%
7 STEATORRHOEA 1,647
5.1%
8 FLATULENCE 1,617
5.0%
9 ABDOMINAL PAIN UPPER 1,366
4.2%
10 HEADACHE 1,113
3.5%
11 ABDOMINAL DISTENSION 1,004
3.1%
12 NAUSEA 948
2.9%
13 TREATMENT NONCOMPLIANCE 805
2.5%
14 MALAISE 782
2.4%
15 ABDOMINAL PAIN 693
2.2%
16 FREQUENT BOWEL MOVEMENTS 639
2.0%
17 PRODUCT QUALITY ISSUE 632
2.0%
18 PHARMACEUTICAL PRODUCT COMPLAINT 616
1.9%
19 DIZZINESS 605
1.9%
20 FAECES DISCOLOURED 600
1.9%
21 VOMITING 591
1.8%
22 FATIGUE 534
1.7%
23 PAIN 474
1.5%
24 MUSCLE SPASMS 436
1.4%
25 RECTAL HAEMORRHAGE 414
1.3%
26 DYSPNOEA 343
1.1%
27 ILL-DEFINED DISORDER 337
1.0%
28 RASH 331
1.0%
29 HAEMATOCHEZIA 327
1.0%
30 DRUG INTERACTION 321
1.0%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.