Oxaliplatin

Common brands: Efudex, Tolak, Fluorouracil, Xeloda, Avastin

Top reporter: Accord Healthcare Inc.

Platinum-based Drug [EPC]Nucleoside Metabolic Inhibitor [EPC]Vascular Endothelial Growth Factor Inhibitor [EPC]Corticosteroid [EPC]Epidermal Growth Factor Receptor Antagonist [EPC]
71,866
Total Reports
36,751
Serious Reports
10,538
Death Reports
30
Reported Reactions
Death Report Ratio: High (14.66%)

Patient Demographics

Male
36,146
Female
24,991

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Oxaliplatin.

# Reaction Reports % of Total
1 DIARRHOEA 6,739
8.7%
2 NAUSEA 5,280
6.8%
3 OFF LABEL USE 4,512
5.8%
4 VOMITING 4,300
5.5%
5 DISEASE PROGRESSION 4,235
5.5%
6 NEUROPATHY PERIPHERAL 4,158
5.4%
7 NEUTROPENIA 4,129
5.3%
8 THROMBOCYTOPENIA 3,459
4.5%
9 DYSPNOEA 2,999
3.9%
10 PYREXIA 2,819
3.6%
11 FATIGUE 2,697
3.5%
12 ANAEMIA 2,365
3.0%
13 ASTHENIA 2,312
3.0%
14 DEATH 2,290
2.9%
15 DRUG INEFFECTIVE 2,096
2.7%
16 DECREASED APPETITE 2,078
2.7%
17 ABDOMINAL PAIN 1,985
2.6%
18 FEBRILE NEUTROPENIA 1,782
2.3%
19 MALIGNANT NEOPLASM PROGRESSION 1,621
2.1%
20 MYELOSUPPRESSION 1,611
2.1%
21 PARAESTHESIA 1,588
2.0%
22 RASH 1,563
2.0%
23 NEUROTOXICITY 1,456
1.9%
24 DEHYDRATION 1,441
1.9%
25 HYPERTENSION 1,417
1.8%
26 PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME 1,379
1.8%
27 ERYTHEMA 1,377
1.8%
28 MALAISE 1,368
1.8%
29 HYPOTENSION 1,351
1.7%
30 LEUKOPENIA 1,297
1.7%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.