Palbociclib

Common brands: Ibrance, Femara, Letrozole, Faslodex, Cligavyx

Top reporter: Pfizer Laboratories Div Pfizer Inc

Kinase Inhibitor [EPC]Aromatase Inhibitor [EPC]Estrogen Receptor Antagonist [EPC]RANK Ligand Inhibitor [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]
94,183
Total Reports
46,263
Serious Reports
10,456
Death Reports
30
Reported Reactions
Death Report Ratio: High (11.10%)

Patient Demographics

Male
2,256
Female
87,055

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Palbociclib.

# Reaction Reports % of Total
1 FATIGUE 15,648
11.8%
2 WHITE BLOOD CELL COUNT DECREASED 11,381
8.6%
3 NEOPLASM PROGRESSION 10,620
8.0%
4 NAUSEA 8,502
6.4%
5 DEATH 7,792
5.9%
6 NEUTROPENIA 6,663
5.0%
7 ALOPECIA 6,343
4.8%
8 DIARRHOEA 5,928
4.5%
9 ASTHENIA 3,762
2.8%
10 OFF LABEL USE 3,656
2.7%
11 DECREASED APPETITE 3,469
2.6%
12 PAIN 3,464
2.6%
13 MALAISE 3,342
2.5%
14 DYSPNOEA 3,263
2.5%
15 VOMITING 3,134
2.4%
16 ARTHRALGIA 3,083
2.3%
17 STOMATITIS 2,803
2.1%
18 CONSTIPATION 2,779
2.1%
19 HEADACHE 2,754
2.1%
20 DIZZINESS 2,520
1.9%
21 MALIGNANT NEOPLASM PROGRESSION 2,324
1.7%
22 COUGH 2,317
1.7%
23 RASH 2,314
1.7%
24 PLATELET COUNT DECREASED 2,287
1.7%
25 DISEASE PROGRESSION 2,272
1.7%
26 NEUTROPHIL COUNT DECREASED 2,260
1.7%
27 ANAEMIA 2,256
1.7%
28 PRODUCT DOSE OMISSION ISSUE 2,184
1.6%
29 FULL BLOOD COUNT DECREASED 1,980
1.5%
30 WEIGHT DECREASED 1,969
1.5%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.