Posaconazole

Common brands: Noxafil, Zovirax, Acyclovir, Acyclovir Suspension, Avaclyr

Top reporter: Merck Sharp & Dohme Llc

Azole Antifungal [EPC]Corticosteroid [EPC]Nucleoside Metabolic Inhibitor [EPC]Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor [EPC]Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor [EPC]
15,720
Total Reports
9,313
Serious Reports
3,791
Death Reports
30
Reported Reactions
Death Report Ratio: High (24.12%)

Patient Demographics

Male
8,152
Female
5,610

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Posaconazole.

# Reaction Reports % of Total
1 OFF LABEL USE 1,593
9.5%
2 DRUG INEFFECTIVE 1,457
8.7%
3 FEBRILE NEUTROPENIA 1,039
6.2%
4 PRODUCT USE IN UNAPPROVED INDICATION 977
5.8%
5 DEATH 958
5.7%
6 DRUG INTERACTION 952
5.7%
7 PYREXIA 870
5.2%
8 NEUTROPENIA 724
4.3%
9 PNEUMONIA 665
4.0%
10 THROMBOCYTOPENIA 515
3.1%
11 DIARRHOEA 507
3.0%
12 NAUSEA 492
2.9%
13 SEPTIC SHOCK 450
2.7%
14 CONDITION AGGRAVATED 432
2.6%
15 ACUTE KIDNEY INJURY 419
2.5%
16 SEPSIS 418
2.5%
17 FATIGUE 405
2.4%
18 PANCYTOPENIA 370
2.2%
19 DYSPNOEA 324
1.9%
20 VOMITING 324
1.9%
21 ACUTE MYELOID LEUKAEMIA 310
1.9%
22 ANAEMIA 297
1.8%
23 INFECTION 292
1.7%
24 HYPOKALAEMIA 289
1.7%
25 PLATELET COUNT DECREASED 288
1.7%
26 ASTHENIA 287
1.7%
27 DISEASE PROGRESSION 284
1.7%
28 PRODUCT USE ISSUE 273
1.6%
29 RESPIRATORY FAILURE 273
1.6%
30 RENAL FAILURE 268
1.6%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.