Raltegravir

Common brands: Isentress, Norvir, Truvada, Prezista, Epivir

Top reporter: Merck Sharp & Dohme Llc

Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]Cytochrome P450 3A Inhibitor [EPC]Protease Inhibitor [EPC]Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]
16,361
Total Reports
4,410
Serious Reports
1,621
Death Reports
30
Reported Reactions
Death Report Ratio: High (9.91%)

Patient Demographics

Male
9,245
Female
4,867

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Raltegravir.

# Reaction Reports % of Total
1 DRUG INTERACTION 1,207
7.0%
2 FOETAL EXPOSURE DURING PREGNANCY 1,076
6.2%
3 DEPRESSION 1,016
5.9%
4 ANXIETY 966
5.6%
5 PAIN 917
5.3%
6 EMOTIONAL DISTRESS 789
4.6%
7 EXPOSURE DURING PREGNANCY 733
4.2%
8 MATERNAL EXPOSURE DURING PREGNANCY 732
4.2%
9 ANHEDONIA 708
4.1%
10 VIROLOGIC FAILURE 582
3.4%
11 RENAL FAILURE 558
3.2%
12 CHRONIC KIDNEY DISEASE 547
3.2%
13 FATIGUE 530
3.1%
14 DIARRHOEA 525
3.0%
15 NAUSEA 469
2.7%
16 OFF LABEL USE 467
2.7%
17 DEATH 465
2.7%
18 ANAEMIA 453
2.6%
19 RENAL IMPAIRMENT 442
2.6%
20 OSTEOPOROSIS 430
2.5%
21 DRUG INEFFECTIVE 419
2.4%
22 PYREXIA 413
2.4%
23 ACUTE KIDNEY INJURY 399
2.3%
24 PATHOGEN RESISTANCE 389
2.2%
25 NO ADVERSE EVENT 357
2.1%
26 LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES 352
2.0%
27 DRUG RESISTANCE 340
2.0%
28 RASH 340
2.0%
29 VOMITING 339
2.0%
30 ASTHENIA 338
2.0%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.