Tapentadol

Common brands: Nucynta Er, Nucynta, Oxycodone Hydrochloride, Oxycontin, Percocet

Top reporter: Collegium Pharmaceutical, Inc.

Partial Opioid Agonist [EPC]Opioid Agonist [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]Benzodiazepine [EPC]Corticosteroid [EPC]
33,133
Total Reports
22,808
Serious Reports
20,544
Death Reports
30
Reported Reactions
Death Report Ratio: High (62.00%)

Patient Demographics

Male
3,171
Female
5,495

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Tapentadol.

# Reaction Reports % of Total
1 DEATH 11,642
28.6%
2 TOXICITY TO VARIOUS AGENTS 9,734
23.9%
3 OVERDOSE 5,886
14.5%
4 DRUG ABUSE 1,549
3.8%
5 DRUG DEPENDENCE 1,065
2.6%
6 DRUG INEFFECTIVE 1,011
2.5%
7 DRUG WITHDRAWAL SYNDROME NEONATAL 944
2.3%
8 PAIN 750
1.8%
9 NAUSEA 722
1.8%
10 ACCIDENTAL OVERDOSE 705
1.7%
11 FATIGUE 441
1.1%
12 HEADACHE 410
1.0%
13 DIZZINESS 409
1.0%
14 INTENTIONAL PRODUCT MISUSE 398
1.0%
15 SOMNOLENCE 388
1.0%
16 VOMITING 387
1.0%
17 DRUG INTERACTION 359
0.9%
18 DYSPNOEA 358
0.9%
19 CONSTIPATION 326
0.8%
20 FALL 323
0.8%
21 DIARRHOEA 318
0.8%
22 OFF LABEL USE 316
0.8%
23 MALAISE 300
0.7%
24 CONFUSIONAL STATE 295
0.7%
25 DEPRESSION 290
0.7%
26 DRUG WITHDRAWAL SYNDROME 289
0.7%
27 ANXIETY 281
0.7%
28 FEELING ABNORMAL 270
0.7%
29 ASTHENIA 268
0.7%
30 MEDICATION ERROR 267
0.7%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.