Temozolomide

Common brands: Temodar, Avastin, Dexamethasone 1.5 Mg, Ozurdex, Dexamethasone

Top reporter: Merck Sharp & Dohme Llc

Alkylating Drug [EPC]Corticosteroid [EPC]Vascular Endothelial Growth Factor Inhibitor [EPC]Nucleoside Metabolic Inhibitor [EPC]Topoisomerase Inhibitor [EPC]
20,653
Total Reports
10,277
Serious Reports
4,341
Death Reports
30
Reported Reactions
Death Report Ratio: High (21.02%)

Patient Demographics

Male
9,413
Female
8,021

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Temozolomide.

# Reaction Reports % of Total
1 DISEASE PROGRESSION 1,875
7.6%
2 OFF LABEL USE 1,736
7.0%
3 DEATH 1,730
7.0%
4 THROMBOCYTOPENIA 1,559
6.3%
5 PRODUCT USE IN UNAPPROVED INDICATION 1,426
5.8%
6 NAUSEA 1,297
5.2%
7 DRUG INEFFECTIVE 1,249
5.1%
8 NEUTROPENIA 1,026
4.1%
9 FATIGUE 1,025
4.1%
10 VOMITING 972
3.9%
11 MALIGNANT NEOPLASM PROGRESSION 910
3.7%
12 FEBRILE NEUTROPENIA 821
3.3%
13 DIARRHOEA 777
3.1%
14 ANAEMIA 755
3.1%
15 ASTHENIA 639
2.6%
16 PLATELET COUNT DECREASED 619
2.5%
17 PYREXIA 619
2.5%
18 INFECTION 565
2.3%
19 HEADACHE 553
2.2%
20 PANCYTOPENIA 500
2.0%
21 CONSTIPATION 461
1.9%
22 SEIZURE 456
1.8%
23 NEOPLASM PROGRESSION 440
1.8%
24 PNEUMONIA 425
1.7%
25 PULMONARY EMBOLISM 419
1.7%
26 HAEMORRHAGE 401
1.6%
27 ATRIAL FIBRILLATION 376
1.5%
28 CONFUSIONAL STATE 375
1.5%
29 LYMPHOPENIA 364
1.5%
30 CYTOPENIA 355
1.4%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.