Voriconazole

Common brands: Vfend, Ambisome, Prograf, Envarsus Xr, Tacrolimus

Top reporter: Roerig

Azole Antifungal [EPC]Corticosteroid [EPC]Polyene Antifungal [EPC]Calcineurin Inhibitor Immunosuppressant [EPC]Lipid-based Polyene Antifungal [EPC]
29,781
Total Reports
15,539
Serious Reports
8,746
Death Reports
30
Reported Reactions
Death Report Ratio: High (29.37%)

Patient Demographics

Male
16,157
Female
10,354

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Voriconazole.

# Reaction Reports % of Total
1 DRUG INEFFECTIVE 4,177
13.9%
2 OFF LABEL USE 2,400
8.0%
3 DRUG INTERACTION 2,340
7.8%
4 DEATH 1,466
4.9%
5 PYREXIA 1,428
4.8%
6 PNEUMONIA 1,333
4.4%
7 CONDITION AGGRAVATED 1,113
3.7%
8 BRONCHOPULMONARY ASPERGILLOSIS 1,038
3.5%
9 FEBRILE NEUTROPENIA 895
3.0%
10 ASPERGILLUS INFECTION 885
2.9%
11 RESPIRATORY FAILURE 841
2.8%
12 NAUSEA 768
2.6%
13 DIARRHOEA 765
2.5%
14 DYSPNOEA 739
2.5%
15 PRODUCT USE IN UNAPPROVED INDICATION 731
2.4%
16 NEUTROPENIA 716
2.4%
17 SEPSIS 699
2.3%
18 HALLUCINATION 690
2.3%
19 SEPTIC SHOCK 680
2.3%
20 MULTIPLE ORGAN DYSFUNCTION SYNDROME 654
2.2%
21 ACUTE KIDNEY INJURY 639
2.1%
22 PHOTOSENSITIVITY REACTION 618
2.1%
23 DRUG LEVEL INCREASED 596
2.0%
24 DRUG RESISTANCE 579
1.9%
25 VOMITING 576
1.9%
26 FUNGAL INFECTION 559
1.9%
27 PANCYTOPENIA 551
1.8%
28 ANAEMIA 533
1.8%
29 DISEASE PROGRESSION 525
1.7%
30 RENAL FAILURE 523
1.7%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.