Abemaciclib

Common brands: Verzenio, Femara, Letrozole, Faslodex, Cligavyx

Top reporter: Eli Lilly And Company

Kinase Inhibitor [EPC]Aromatase Inhibitor [EPC]Estrogen Receptor Antagonist [EPC]RANK Ligand Inhibitor [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]
18,718
Total Reports
13,866
Serious Reports
1,388
Death Reports
30
Reported Reactions
Death Report Ratio: High (7.42%)

Patient Demographics

Male
432
Female
16,366

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Abemaciclib.

# Reaction Reports % of Total
1 DIARRHOEA 5,680
22.1%
2 FATIGUE 2,311
9.0%
3 NAUSEA 1,967
7.6%
4 VOMITING 1,055
4.1%
5 MALIGNANT NEOPLASM PROGRESSION 1,040
4.0%
6 DECREASED APPETITE 875
3.4%
7 ASTHENIA 783
3.0%
8 DEATH 753
2.9%
9 DRUG INEFFECTIVE 714
2.8%
10 WHITE BLOOD CELL COUNT DECREASED 655
2.5%
11 ANAEMIA 651
2.5%
12 CONSTIPATION 635
2.5%
13 ABDOMINAL PAIN UPPER 611
2.4%
14 NEUTROPENIA 596
2.3%
15 ALOPECIA 542
2.1%
16 HEADACHE 520
2.0%
17 DEHYDRATION 512
2.0%
18 ARTHRALGIA 505
2.0%
19 ABDOMINAL PAIN 502
2.0%
20 PAIN 499
1.9%
21 DYSPNOEA 496
1.9%
22 OFF LABEL USE 494
1.9%
23 MYELOSUPPRESSION 493
1.9%
24 WEIGHT DECREASED 469
1.8%
25 PRODUCT DOSE OMISSION ISSUE 448
1.7%
26 DIZZINESS 435
1.7%
27 BLOOD CREATININE INCREASED 408
1.6%
28 RASH 380
1.5%
29 INTERSTITIAL LUNG DISEASE 354
1.4%
30 ABDOMINAL DISCOMFORT 353
1.4%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.