Ambrisentan

Common brands: Letairis, Adcirca, Remodulin, Revatio, Tyvaso

Top reporter: Gilead Sciences, Inc.

Endothelin Receptor Antagonist [EPC]Prostacycline Vasodilator [EPC]Phosphodiesterase 5 Inhibitor [EPC]Loop Diuretic [EPC]Prostacyclin Receptor Agonist [EPC]
123,381
Total Reports
36,692
Serious Reports
16,948
Death Reports
30
Reported Reactions
Death Report Ratio: High (13.74%)

Patient Demographics

Male
29,394
Female
91,725

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Ambrisentan.

# Reaction Reports % of Total
1 DYSPNOEA 19,051
12.6%
2 DEATH 11,323
7.5%
3 HEADACHE 10,681
7.0%
4 PNEUMONIA 7,230
4.8%
5 DIARRHOEA 7,038
4.6%
6 FATIGUE 6,540
4.3%
7 DIZZINESS 6,495
4.3%
8 NAUSEA 6,476
4.3%
9 FLUID RETENTION 5,450
3.6%
10 MALAISE 5,304
3.5%
11 COUGH 4,576
3.0%
12 OEDEMA PERIPHERAL 4,178
2.8%
13 PERIPHERAL SWELLING 4,008
2.6%
14 CHEST PAIN 3,823
2.5%
15 NASAL CONGESTION 3,791
2.5%
16 HYPOTENSION 3,718
2.5%
17 VOMITING 3,712
2.4%
18 OEDEMA 3,544
2.3%
19 PULMONARY ARTERIAL HYPERTENSION 3,337
2.2%
20 PAIN 3,158
2.1%
21 UNEVALUABLE EVENT 3,151
2.1%
22 PAIN IN EXTREMITY 3,120
2.1%
23 SYNCOPE 3,096
2.0%
24 FALL 2,792
1.8%
25 ASTHENIA 2,775
1.8%
26 OXYGEN SATURATION DECREASED 2,696
1.8%
27 OFF LABEL USE 2,688
1.8%
28 FLUSHING 2,662
1.8%
29 NASOPHARYNGITIS 2,633
1.7%
30 DYSPNOEA EXERTIONAL 2,537
1.7%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.