Aprepitant

Common brands: Emend, Cinvanti, Aponvie, Ozurdex, Dexamethasone

Top reporter: Merck Sharp & Dohme Llc

Substance P/Neurokinin-1 Receptor Antagonist [EPC]Corticosteroid [EPC]Platinum-based Drug [EPC]Serotonin-3 Receptor Antagonist [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]
18,080
Total Reports
7,699
Serious Reports
3,022
Death Reports
30
Reported Reactions
Death Report Ratio: High (16.71%)

Patient Demographics

Male
6,118
Female
10,276

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Aprepitant.

# Reaction Reports % of Total
1 NAUSEA 2,186
6.5%
2 FATIGUE 1,854
5.5%
3 PYREXIA 1,624
4.8%
4 DIARRHOEA 1,583
4.7%
5 DYSPNOEA 1,548
4.6%
6 VOMITING 1,512
4.5%
7 OFF LABEL USE 1,388
4.1%
8 ALOPECIA 1,304
3.9%
9 RASH 1,244
3.7%
10 HYPERSENSITIVITY 1,164
3.4%
11 DECREASED APPETITE 1,070
3.2%
12 FEBRILE NEUTROPENIA 1,061
3.1%
13 PRURITUS 1,052
3.1%
14 STOMATITIS 1,016
3.0%
15 INFUSION RELATED REACTION 1,011
3.0%
16 PAIN 987
2.9%
17 CONFUSIONAL STATE 936
2.8%
18 INFECTION 907
2.7%
19 ASTHENIA 893
2.6%
20 GENERAL PHYSICAL HEALTH DETERIORATION 885
2.6%
21 GASTROINTESTINAL DISORDER 878
2.6%
22 ARTHRALGIA 869
2.6%
23 GLOSSODYNIA 869
2.6%
24 MALAISE 869
2.6%
25 HEPATIC ENZYME INCREASED 851
2.5%
26 HAND DEFORMITY 845
2.5%
27 IMPAIRED HEALING 844
2.5%
28 FOLLICULITIS 841
2.5%
29 HELICOBACTER INFECTION 831
2.5%
30 NASOPHARYNGITIS 822
2.4%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.