PRURITUS

Adverse reaction reported in 577,023 FDA reports across 264 drugs.

577,023

Total Reports

264

Drugs Involved

Dupilumab

Most Reported Drug

Drugs Associated with PRURITUS

Drugs where "PRURITUS" was reported as an adverse event.

#	Drug	Reports	% of Total
1	Dupilumab	52,379	9.1%
2	Prednisone	14,799	2.6%
3	Acetaminophen	14,672	2.5%
4	Aspirin	13,631	2.4%
5	Ergocalciferol	13,032	2.3%
6	Adapalene	11,875	2.1%
7	Ibuprofen	9,576	1.7%
8	Pain Reliever	9,506	1.6%
9	Levothyroxine	9,501	1.6%
10	Secukinumab	9,301	1.6%
11	Pantoprazole	8,787	1.5%
12	Omeprazole	8,069	1.4%
13	Lisinopril	7,832	1.4%
14	Ibupfrofen	7,786	1.3%
15	Cetirizine	7,667	1.3%
16	Lenalidomide	7,297	1.3%
17	Metformin	7,081	1.2%
18	Acetaminophen, Guaifenesin, / Phenylephrine Hydrochloride	6,633	1.1%
19	Omalizumab	6,122	1.1%
20	Amlodipine	5,988	1.0%
21	Simvastatin	5,856	1.0%
22	Atorvastatin	5,656	1.0%
23	Oxycodone	5,641	1.0%
24	Metoprolol	5,384	0.9%
25	Dimethyl	5,061	0.9%
26	Rosuvastatin	4,970	0.9%
27	Losartan	4,968	0.9%
28	Hydrocortisone	4,926	0.9%
29	Calcium	4,921	0.9%
30	Celecoxib	4,688	0.8%
31	Ribavirin	4,642	0.8%
32	Hydrochlorothiazide	4,418	0.8%
33	Cetiirizine	4,307	0.7%
34	Fish Oil	4,303	0.7%
35	Apremilast	4,225	0.7%
36	Peginterferon Alfa-2a	4,224	0.7%
37	Vitamin C	4,185	0.7%
38	Clopidogrel	4,105	0.7%
39	Lansoprazole	4,028	0.7%
40	Methylprednisolone	3,587	0.6%
41	Hydrocortisone 1%	3,556	0.6%
42	Anti Itch	3,551	0.6%
43	Anti-Itch	3,549	0.6%
44	Anti-Pruritic	3,549	0.6%
45	Antipruritic (Anti-Itch)	3,549	0.6%
46	Cool Relief With Aloe	3,549	0.6%
47	Drs Hydrocortisone	3,549	0.6%
48	Hydrocortisone Continuous Spray	3,549	0.6%
49	Hydrocortisone Spray	3,549	0.6%
50	Allopurinol	3,481	0.6%
51	Salicylic Acid	3,462	0.6%
52	Ramipril	3,432	0.6%
53	Loratadine	3,264	0.6%
54	Escitalopram	3,132	0.5%
55	Famotidine	3,097	0.5%
56	Atenolol	3,075	0.5%
57	Hydroxyzine	3,069	0.5%
58	Sulfamethoxazole / Trimethoprim	3,007	0.5%
59	Magnesium	2,998	0.5%
60	Montelukast	2,995	0.5%
61	Naproxen	2,993	0.5%
62	Lamotrigine	2,961	0.5%
63	Bisoprolol	2,935	0.5%
64	Denosumab	2,920	0.5%
65	Diphenhydramine	2,883	0.5%
66	Doxycycline	2,845	0.5%
67	Amoxicillin	2,844	0.5%
68	Doxycycline Hyclate	2,812	0.5%
69	Carvedilol	2,777	0.5%
70	Cyclosporine	2,625	0.5%
71	Risankizumab-Rzaa	2,600	0.5%
72	Fluticasone	2,558	0.4%
73	Estradiol	2,501	0.4%
74	Triamcinolone Acetonide	2,368	0.4%
75	Triamcinolone Acetonide Ointment Usp, 0.05%	2,257	0.4%
76	Valsartan	2,201	0.4%
77	Ezetimibe	2,196	0.4%
78	Acyclovir	2,126	0.4%
79	Meloxicam	2,093	0.4%
80	Epinephrine	2,027	0.4%
81	Clopidogrel Bisulfate	1,966	0.3%
82	Iron	1,952	0.3%
83	Esomeprazole	1,919	0.3%
84	Nivolumab	1,748	0.3%
85	Ruxolitinib	1,728	0.3%
86	Ocrelizumab	1,660	0.3%
87	Escitalopram Oxalate	1,597	0.3%
88	Metronidazole	1,528	0.3%
89	Metoroprolol	1,515	0.3%
90	Duloxetine	1,491	0.3%
91	Pomalidomide	1,472	0.3%
92	Infliximab-Dyyb	1,437	0.2%
93	Chlorhexidine Gluconate	1,427	0.2%
94	Estradiol Transdermal	1,382	0.2%
95	Diltiazem	1,311	0.2%
96	Biotin	1,310	0.2%
97	Ribociclib	1,301	0.2%
98	Ursodiol	1,275	0.2%
99	Dapagliflozin	1,259	0.2%
100	Levocetirizine Dihydrochloride	1,252	0.2%
101	Adrenalinum	1,248	0.2%
102	Melatonin	1,246	0.2%
103	Mometasone Furoate	1,240	0.2%
104	Ursosiol	1,232	0.2%
105	Empagliflozin	1,230	0.2%
106	Multivitamin	1,222	0.2%
107	Glipizide	1,198	0.2%
108	Cabozantinib	1,192	0.2%
109	Glatiramer	1,189	0.2%
110	Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	1,187	0.2%
111	Ascorbic Acid	1,146	0.2%
112	Nilotinib	1,128	0.2%
113	Fenofibrate	1,124	0.2%
114	Irbesartan	1,123	0.2%
115	Cyanocobalamin	1,116	0.2%
116	Teriflunomide	1,108	0.2%
117	Finasteride	1,091	0.2%
118	Vancomycin	1,091	0.2%
119	Vitamin E	1,091	0.2%
120	Pirfenidone	1,065	0.2%
121	Doxyclycline Hyclate	1,065	0.2%
122	Estrogens, Conjugated	1,056	0.2%
123	Aprepitant	1,052	0.2%
124	Anastrozole	1,040	0.2%
125	Conjugated Estrogens	1,031	0.2%
126	Sevelamer Carbonate	1,008	0.2%
127	Minoxidil	1,001	0.2%
128	Oxybutynin	995	0.2%
129	Nemolizumab-Ilto	994	0.2%
130	Zinc Gluconate	969	0.2%
131	Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol / Niacinamide	954	0.2%
132	Zinc Chloride	938	0.2%
133	Latanoprost	936	0.2%
134	Zinc	936	0.2%
135	Ketoconazole	936	0.2%
136	Mometasone	931	0.2%
137	Olmesartan Medoxomil	928	0.2%
138	Clindamycin	923	0.2%
139	Ipilimumab	905	0.2%
140	Clarithromycin	892	0.2%
141	Iohexol	874	0.2%
142	Amoxicillin / Clavulanate Potassium	848	0.1%
143	Clobetasol	819	0.1%
144	Amitriptyline	817	0.1%
145	Clobetasol Propionate Ointment Usp, 0.05%	817	0.1%
146	Fexofenadine	812	0.1%
147	Nicotine	800	0.1%
148	Ixekizumab	787	0.1%
149	Glimepiride	784	0.1%
150	Methoxy Polyethylene Glycol-Epoetin Beta	781	0.1%
151	Ketoconazole Foam	778	0.1%
152	Vortioxetine	776	0.1%
153	Isosorbide Dinitrate	767	0.1%
154	Valacyclovir	752	0.1%
155	Cephalexin	750	0.1%
156	Isosorbide Mononitrate	735	0.1%
157	Linagliptin	730	0.1%
158	Exemestane	728	0.1%
159	Fosaprepitant Dimeglumine	721	0.1%
160	Sumatriptan	715	0.1%
161	Sofosbuvir	708	0.1%
162	Alirocumab	696	0.1%
163	Cetuximab	685	0.1%
164	Tamsulosin	683	0.1%
165	Guaifenesin	682	0.1%
166	Telmisartan	676	0.1%
167	Candesartan Cilexetil	673	0.1%
168	Dimenhydrinate	666	0.1%
169	Glecaprevir / Pibrentasvir	654	0.1%
170	Omega-3-Acid Ethyl Esters	652	0.1%
171	Pravastatin	650	0.1%
172	Sulfur	650	0.1%
173	Guselkumab	639	0.1%
174	Erythromycin	639	0.1%
175	Lovastatin	633	0.1%
176	Crisaborole	633	0.1%
177	Felodipine	628	0.1%
178	Felodipine Extended-	628	0.1%
179	Dutasteride	616	0.1%
180	Indomethacin	615	0.1%
181	Iron Sucrose	614	0.1%
182	Pertuzumab	609	0.1%
183	Rabeprazole	606	0.1%
184	Progesterone	604	0.1%
185	Alemtuzumab	600	0.1%
186	Sorafenib	594	0.1%
187	Diroximel	580	0.1%
188	Methocarbamol	561	0.1%
189	Ceftriaxone	545	0.1%
190	Mupirocin	537	0.1%
191	Nitrofurantoin (Monohydrate / Macrocrystals)	521	0.1%
192	Nitrofurantoin Monohydrate / Macrocrystals	521	0.1%
193	Nitrofurantoin	508	0.1%
194	Bimekizumab	502	0.1%
195	Naproxen Sodium, Pseudoephedrine Hydrochloride	490	0.1%
196	Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	490	0.1%
197	Azelastine	488	0.1%
198	Calcitriol	476	0.1%
199	Doxepin	475	0.1%
200	Galcanezumab-Gnlm	472	0.1%
201	Solifenacin	472	0.1%
202	Sitagliptin / Metformin Hydrochloride	455	0.1%
203	Benralizumab	448	0.1%
204	Trimethoprim	446	0.1%
205	Linaclotide	439	0.1%
206	Imatinib	436	0.1%
207	Pitavastatin	429	0.1%
208	Desloratadine	426	0.1%
209	Bimatoprost	425	0.1%
210	Panitumumab	410	0.1%
211	Terbinafine	407	0.1%
212	Ezetimibe / Simvastatin	400	0.1%
213	Eszopiclone	398	0.1%
214	Minoxidil Foam 5% (Womens)	393	0.1%
215	Cinacalcet	391	0.1%
216	Erythropoietin	391	0.1%
217	Vemurafenib	386	0.1%
218	Cholestyramine	376	0.1%
219	Lapatinib	368	0.1%
220	Clotrimazole	359	0.1%
221	Chlorthalidone	353	0.1%
222	Niacin	345	0.1%
223	Drs Clotrimazole	345	0.1%
224	Family Wellness Clotrimazole	345	0.1%
225	Fremanezumab-Vfrm	343	0.1%
226	Brimonidine	336	0.1%
227	Sotalol	334	0.1%
228	Valsartan / Hydrochlorothiazide	334	0.1%
229	Dextrose	330	0.1%
230	Pegvaliase-Pqpz	330	0.1%
231	Thyroid, Porcine	327	0.1%
232	Losartan Potassium / Hydrochlorothiazide	326	0.1%
233	Brinzolamide	315	0.1%
234	Rifampin	312	0.1%
235	Buspirone	311	0.1%
236	Cimetidine	311	0.1%
237	Epoetin Alfa	300	0.1%
238	Ledipasvir / Sofosbuvir	297	0.1%
239	Eptinezumab-Jjmr	296	0.1%
240	Avapritinib	295	0.1%
241	Lisinopril / Hydrochlorothiazide	294	0.1%
242	Tretinoin	283	0.0%
243	Alpelisib	277	0.0%
244	Apalutamide	270	0.0%
245	Colesevelam	269	0.0%
246	Voxelotor	264	0.0%
247	Amlodipine Besylate / Benazepril Hydrochloride	252	0.0%
248	Rimegepant	245	0.0%
249	Primidone	245	0.0%
250	Acetylcysteine	238	0.0%
251	Oxybutynin Chloride	237	0.0%
252	Dapsone	235	0.0%
253	Vilazodone	229	0.0%
254	Amlodipine Besylate / Valsartan	206	0.0%
255	Velpatasvir / Sofosbuvir	199	0.0%
256	Agalsidase Beta	199	0.0%
257	Miconazole Nitrate	195	0.0%
258	Daspone	190	0.0%
259	Prasugrel	187	0.0%
260	Cefazolin	184	0.0%
261	Terazosin	182	0.0%
262	Bosutinib	175	0.0%
263	Gefitinib	174	0.0%
264	Encorafenib	164	0.0%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. The presence of a drug in this list does not mean the drug caused pruritus. Always consult your healthcare provider.