Crizotinib

Common brands: Xalkori, Dexamethasone, Dexamethasone 1.5 Mg, Dextenza, Dexycu

Top reporter: Pfizer Laboratories Div Pfizer Inc

Kinase Inhibitor [EPC]Corticosteroid [EPC]Platinum-based Drug [EPC]Folate Analog Metabolic Inhibitor [EPC]Benzodiazepine [EPC]
12,556
Total Reports
5,423
Serious Reports
3,761
Death Reports
30
Reported Reactions
Death Report Ratio: High (29.95%)

Patient Demographics

Male
5,062
Female
6,158

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Crizotinib.

# Reaction Reports % of Total
1 DEATH 2,296
15.2%
2 DISEASE PROGRESSION 1,215
8.0%
3 NAUSEA 1,115
7.4%
4 NEOPLASM PROGRESSION 1,112
7.3%
5 DIARRHOEA 843
5.6%
6 VOMITING 790
5.2%
7 FATIGUE 553
3.7%
8 OFF LABEL USE 469
3.1%
9 OEDEMA PERIPHERAL 443
2.9%
10 CONSTIPATION 438
2.9%
11 DYSPNOEA 428
2.8%
12 LUNG NEOPLASM MALIGNANT 418
2.8%
13 VISUAL IMPAIRMENT 404
2.7%
14 DECREASED APPETITE 378
2.5%
15 ASTHENIA 338
2.2%
16 PNEUMONIA 334
2.2%
17 DIZZINESS 313
2.1%
18 MALAISE 312
2.1%
19 PLEURAL EFFUSION 306
2.0%
20 MALIGNANT NEOPLASM PROGRESSION 293
1.9%
21 PERIPHERAL SWELLING 292
1.9%
22 NON-SMALL CELL LUNG CANCER 281
1.9%
23 PYREXIA 262
1.7%
24 COUGH 249
1.6%
25 NEOPLASM MALIGNANT 222
1.5%
26 DRUG INEFFECTIVE 220
1.5%
27 RASH 207
1.4%
28 DYSGEUSIA 204
1.3%
29 OEDEMA 202
1.3%
30 WEIGHT DECREASED 194
1.3%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.