Cyclosporine

Common brands: Restasis, Neoral, Cequa, Sandimmune, Gengraf

Top reporter: Allergan, Inc.

Calcineurin Inhibitor Immunosuppressant [EPC]Corticosteroid [EPC]Folate Analog Metabolic Inhibitor [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]Alkylating Drug [EPC]
108,543
Total Reports
48,152
Serious Reports
14,248
Death Reports
30
Reported Reactions
Death Report Ratio: High (13.13%)

Patient Demographics

Male
37,082
Female
58,727

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Cyclosporine.

# Reaction Reports % of Total
1 DRUG INEFFECTIVE 12,592
12.0%
2 OFF LABEL USE 9,164
8.7%
3 EYE IRRITATION 7,904
7.5%
4 PRODUCT USE IN UNAPPROVED INDICATION 4,265
4.1%
5 PYREXIA 4,108
3.9%
6 EYE PAIN 3,843
3.7%
7 NAUSEA 3,670
3.5%
8 DIARRHOEA 3,629
3.5%
9 HEADACHE 3,623
3.5%
10 FATIGUE 3,407
3.2%
11 PNEUMONIA 3,327
3.2%
12 PAIN 3,173
3.0%
13 CONDITION AGGRAVATED 3,150
3.0%
14 VISION BLURRED 2,872
2.7%
15 RASH 2,678
2.6%
16 PRURITUS 2,625
2.5%
17 DYSPNOEA 2,581
2.5%
18 DEATH 2,464
2.3%
19 OCULAR HYPERAEMIA 2,414
2.3%
20 ARTHRALGIA 2,384
2.3%
21 HYPERTENSION 2,359
2.2%
22 VOMITING 2,316
2.2%
23 CYTOMEGALOVIRUS INFECTION 2,242
2.1%
24 DRY EYE 2,135
2.0%
25 RENAL IMPAIRMENT 2,120
2.0%
26 SEPSIS 2,118
2.0%
27 BLOOD CREATININE INCREASED 2,014
1.9%
28 INFECTION 1,995
1.9%
29 MALAISE 1,945
1.9%
30 RENAL FAILURE 1,878
1.8%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.