Febuxostat

Common brands: Uloric, Lasix, Furosemide, Lasix Onyu, Aspirin 325

Top reporter: Takeda Pharmaceuticals America, Inc.

Xanthine Oxidase Inhibitor [EPC]Loop Diuretic [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]Corticosteroid [EPC]Proton Pump Inhibitor [EPC]
16,332
Total Reports
7,917
Serious Reports
2,141
Death Reports
30
Reported Reactions
Death Report Ratio: High (13.11%)

Patient Demographics

Male
9,703
Female
4,675

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Febuxostat.

# Reaction Reports % of Total
1 DIARRHOEA 863
5.4%
2 NAUSEA 846
5.3%
3 ACUTE KIDNEY INJURY 845
5.3%
4 RASH 793
5.0%
5 OFF LABEL USE 738
4.6%
6 GOUT 691
4.3%
7 DRUG INEFFECTIVE 683
4.3%
8 DYSPNOEA 634
4.0%
9 FATIGUE 613
3.8%
10 ANAEMIA 584
3.7%
11 HEADACHE 582
3.6%
12 PNEUMONIA 545
3.4%
13 PYREXIA 538
3.4%
14 DEATH 522
3.3%
15 RENAL IMPAIRMENT 506
3.2%
16 CHRONIC KIDNEY DISEASE 472
3.0%
17 RENAL FAILURE 459
2.9%
18 DECREASED APPETITE 453
2.8%
19 ARTHRALGIA 452
2.8%
20 PAIN 420
2.6%
21 CARDIAC FAILURE 411
2.6%
22 BLOOD CREATININE INCREASED 403
2.5%
23 MALAISE 398
2.5%
24 CONDITION AGGRAVATED 380
2.4%
25 DIZZINESS 379
2.4%
26 FALL 363
2.3%
27 ASPARTATE AMINOTRANSFERASE INCREASED 361
2.3%
28 ALANINE AMINOTRANSFERASE INCREASED 352
2.2%
29 DRUG HYPERSENSITIVITY 346
2.2%
30 OEDEMA PERIPHERAL 338
2.1%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.