Lamivudine

Common brands: Epivir, Retrovir, Zidovudine, Viread, Norvir

Top reporter: Viiv Healthcare Company

Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]Protease Inhibitor [EPC]Cytochrome P450 3A Inhibitor [EPC]
30,530
Total Reports
9,944
Serious Reports
4,060
Death Reports
30
Reported Reactions
Death Report Ratio: High (13.30%)

Patient Demographics

Male
14,497
Female
8,331

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Lamivudine.

# Reaction Reports % of Total
1 FOETAL EXPOSURE DURING PREGNANCY 2,014
6.2%
2 VIROLOGIC FAILURE 1,951
6.0%
3 DRUG RESISTANCE 1,943
6.0%
4 DRUG INTERACTION 1,858
5.7%
5 PATHOGEN RESISTANCE 1,724
5.3%
6 VIRAL MUTATION IDENTIFIED 1,666
5.2%
7 DEPRESSION 1,337
4.1%
8 PYREXIA 1,273
3.9%
9 DRUG INEFFECTIVE 1,140
3.5%
10 ANAEMIA 1,118
3.5%
11 PAIN 1,112
3.4%
12 NAUSEA 1,057
3.3%
13 TREATMENT FAILURE 1,014
3.1%
14 VOMITING 1,005
3.1%
15 ANXIETY 986
3.1%
16 EXPOSURE DURING PREGNANCY 863
2.7%
17 DIARRHOEA 840
2.6%
18 RENAL FAILURE 839
2.6%
19 EMOTIONAL DISTRESS 807
2.5%
20 RENAL IMPAIRMENT 785
2.4%
21 FATIGUE 769
2.4%
22 DEATH 759
2.3%
23 OFF LABEL USE 756
2.3%
24 IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME 755
2.3%
25 ANHEDONIA 711
2.2%
26 CONDITION AGGRAVATED 706
2.2%
27 CHRONIC KIDNEY DISEASE 654
2.0%
28 DRUG EXPOSURE DURING PREGNANCY 630
1.9%
29 IMMUNE RECONSTITUTION SYNDROME 626
1.9%
30 TREATMENT NONCOMPLIANCE 626
1.9%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.