Lopinavir / Ritonavir

Common brands: Kaletra, Epivir, Truvada, Lamivudine, Viread

Top reporter: Abbvie Inc.

Cytochrome P450 3A Inhibitor [EPC]Protease Inhibitor [EPC]Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]Benzodiazepine [EPC]
13,443
Total Reports
3,269
Serious Reports
1,766
Death Reports
30
Reported Reactions
Death Report Ratio: High (13.14%)

Patient Demographics

Male
7,696
Female
4,477

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Lopinavir / Ritonavir.

# Reaction Reports % of Total
1 DRUG INTERACTION 1,334
8.3%
2 DEPRESSION 1,133
7.0%
3 NAUSEA 781
4.9%
4 DRUG EXPOSURE DURING PREGNANCY 780
4.8%
5 DIARRHOEA 775
4.8%
6 FOETAL EXPOSURE DURING PREGNANCY 750
4.7%
7 ANXIETY 713
4.4%
8 VOMITING 701
4.4%
9 PAIN 693
4.3%
10 OFF LABEL USE 675
4.2%
11 EMOTIONAL DISTRESS 578
3.6%
12 RENAL FAILURE 542
3.4%
13 PYREXIA 526
3.3%
14 ANHEDONIA 510
3.2%
15 ANAEMIA 450
2.8%
16 CHRONIC KIDNEY DISEASE 431
2.7%
17 ABORTION SPONTANEOUS 420
2.6%
18 PNEUMONIA 415
2.6%
19 OSTEOPOROSIS 400
2.5%
20 LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES 347
2.2%
21 PREMATURE BABY 342
2.1%
22 FATIGUE 336
2.1%
23 BONE DENSITY DECREASED 335
2.1%
24 ASTHENIA 332
2.1%
25 MATERNAL EXPOSURE DURING PREGNANCY 306
1.9%
26 PSYCHOTIC DISORDER 301
1.9%
27 EXPOSURE DURING PREGNANCY 299
1.9%
28 CONDITION AGGRAVATED 295
1.8%
29 RENAL FAILURE ACUTE 293
1.8%
30 BLOOD BILIRUBIN INCREASED 292
1.8%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.