Olaparib

Common brands: Lynparza, Avastin, Carboplatin, Kyxata, Abraxane

Top reporter: Astrazeneca Pharmaceuticals Lp

Poly(ADP-Ribose) Polymerase Inhibitor [EPC]Vascular Endothelial Growth Factor Inhibitor [EPC]Platinum-based Drug [EPC]Microtubule Inhibitor [EPC]Corticosteroid [EPC]
20,092
Total Reports
15,002
Serious Reports
5,804
Death Reports
30
Reported Reactions
Death Report Ratio: High (28.89%)

Patient Demographics

Male
4,103
Female
14,192

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Olaparib.

# Reaction Reports % of Total
1 DEATH 4,629
20.0%
2 MALIGNANT NEOPLASM PROGRESSION 2,008
8.7%
3 NAUSEA 1,755
7.6%
4 FATIGUE 1,667
7.2%
5 ANAEMIA 1,569
6.8%
6 OFF LABEL USE 904
3.9%
7 VOMITING 704
3.0%
8 DRUG INEFFECTIVE 663
2.9%
9 DIARRHOEA 600
2.6%
10 ASTHENIA 575
2.5%
11 NEUROPATHY PERIPHERAL 570
2.5%
12 DECREASED APPETITE 526
2.3%
13 DISEASE PROGRESSION 492
2.1%
14 MYELODYSPLASTIC SYNDROME 472
2.0%
15 HAEMOGLOBIN DECREASED 425
1.8%
16 MYELOSUPPRESSION 411
1.8%
17 CONSTIPATION 408
1.8%
18 HEADACHE 395
1.7%
19 PLATELET COUNT DECREASED 389
1.7%
20 DYSPNOEA 387
1.7%
21 PAIN 381
1.6%
22 INTERSTITIAL LUNG DISEASE 378
1.6%
23 MALAISE 376
1.6%
24 PRODUCT DOSE OMISSION ISSUE 366
1.6%
25 THROMBOCYTOPENIA 359
1.6%
26 DIZZINESS 346
1.5%
27 OVARIAN CANCER RECURRENT 345
1.5%
28 ARTHRALGIA 342
1.5%
29 ACUTE MYELOID LEUKAEMIA 338
1.5%
30 RENAL IMPAIRMENT 328
1.4%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.