Propofol

Common brands: Diprivan, Fentanyl, Fentanyl System, Midazolam, Midazolam In Sodium Chloride

Top reporter: Fresenius Kabi Usa, Llc

General Anesthetic [EPC]Opioid Agonist [EPC]Benzodiazepine [EPC]Corticosteroid [EPC]Nonsteroidal Anti-inflammatory Drug [EPC]
35,665
Total Reports
14,581
Serious Reports
4,868
Death Reports
30
Reported Reactions
Death Report Ratio: High (13.65%)

Patient Demographics

Male
15,589
Female
16,084

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Propofol.

# Reaction Reports % of Total
1 HYPOTENSION 2,865
9.0%
2 DRUG INEFFECTIVE 2,734
8.6%
3 ANAPHYLACTIC SHOCK 2,033
6.4%
4 CARDIAC ARREST 1,800
5.6%
5 ANAPHYLACTIC REACTION 1,669
5.2%
6 OFF LABEL USE 1,655
5.2%
7 DRUG INTERACTION 1,541
4.8%
8 TACHYCARDIA 1,189
3.7%
9 BRADYCARDIA 1,176
3.7%
10 PYREXIA 1,001
3.1%
11 ACUTE KIDNEY INJURY 984
3.1%
12 RHABDOMYOLYSIS 905
2.8%
13 RENAL FAILURE 804
2.5%
14 BRONCHOSPASM 803
2.5%
15 OXYGEN SATURATION DECREASED 799
2.5%
16 TOXICITY TO VARIOUS AGENTS 760
2.4%
17 PAIN 740
2.3%
18 RESPIRATORY FAILURE 726
2.3%
19 SEROTONIN SYNDROME 714
2.2%
20 RASH 692
2.2%
21 NAUSEA 686
2.2%
22 VOMITING 675
2.1%
23 DYSPNOEA 667
2.1%
24 HYPOXIA 653
2.0%
25 BLOOD PRESSURE DECREASED 620
1.9%
26 METABOLIC ACIDOSIS 615
1.9%
27 PROPOFOL INFUSION SYNDROME 610
1.9%
28 CONDITION AGGRAVATED 601
1.9%
29 PRODUCT USE IN UNAPPROVED INDICATION 585
1.8%
30 ERYTHEMA 568
1.8%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.