Pyrazinamide

Common brands: Isoniazid, Rifadin Iv, Rifampin, Zyvox, Linezolid

Top reporter: Ani Pharmaceuticals, Inc.

Antimycobacterial [EPC]Rifamycin Antibacterial [EPC]Fluoroquinolone Antibacterial [EPC]Oxazolidinone Antibacterial [EPC]Corticosteroid [EPC]
9,208
Total Reports
4,075
Serious Reports
1,635
Death Reports
30
Reported Reactions
Death Report Ratio: High (17.76%)

Patient Demographics

Male
4,352
Female
3,509

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Pyrazinamide.

# Reaction Reports % of Total
1 DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS 668
6.6%
2 DRUG-INDUCED LIVER INJURY 647
6.3%
3 PYREXIA 596
5.8%
4 DRUG INTERACTION 586
5.8%
5 PARADOXICAL DRUG REACTION 512
5.0%
6 OFF LABEL USE 503
4.9%
7 DRUG INEFFECTIVE 481
4.7%
8 VOMITING 478
4.7%
9 TUBERCULOSIS 395
3.9%
10 NAUSEA 389
3.8%
11 ANAEMIA 368
3.6%
12 HEPATOTOXICITY 360
3.5%
13 DRUG RESISTANCE 353
3.5%
14 CONDITION AGGRAVATED 326
3.2%
15 NEUROPATHY PERIPHERAL 275
2.7%
16 IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME 259
2.5%
17 HEPATITIS 258
2.5%
18 JAUNDICE 253
2.5%
19 ACUTE HEPATIC FAILURE 235
2.3%
20 PULMONARY TUBERCULOSIS 233
2.3%
21 ALANINE AMINOTRANSFERASE INCREASED 228
2.2%
22 RASH 228
2.2%
23 DIARRHOEA 215
2.1%
24 ELECTROCARDIOGRAM QT PROLONGED 213
2.1%
25 DYSPNOEA 211
2.1%
26 ASPARTATE AMINOTRANSFERASE INCREASED 195
1.9%
27 THROMBOCYTOPENIA 189
1.9%
28 ARTHRALGIA 184
1.8%
29 DISSEMINATED TUBERCULOSIS 180
1.8%
30 PRODUCT USE IN UNAPPROVED INDICATION 172
1.7%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.