Sitagliptin

Common brands: Januvia, Metformin Hydrochloride, Metformin, Zituvio, Aspirin 325

Top reporter: Merck Sharp & Dohme Llc

Nonsteroidal Anti-inflammatory Drug [EPC]Insulin Analog [EPC]Dipeptidyl Peptidase 4 Inhibitor [EPC]Sulfonylurea [EPC]HMG-CoA Reductase Inhibitor [EPC]
70,968
Total Reports
19,402
Serious Reports
6,711
Death Reports
30
Reported Reactions
Death Report Ratio: High (9.46%)

Patient Demographics

Male
30,760
Female
33,583

Reported Adverse Reactions (30)

Side effects reported in FDA adverse event reports for Sitagliptin.

# Reaction Reports % of Total
1 BLOOD GLUCOSE INCREASED 4,472
6.9%
2 NAUSEA 3,853
6.0%
3 DIARRHOEA 3,529
5.5%
4 DRUG INEFFECTIVE 3,487
5.4%
5 FATIGUE 2,935
4.6%
6 HEADACHE 2,539
3.9%
7 DIZZINESS 2,454
3.8%
8 VOMITING 2,377
3.7%
9 DYSPNOEA 2,358
3.7%
10 PANCREATITIS 2,214
3.4%
11 ACUTE KIDNEY INJURY 2,193
3.4%
12 DEATH 2,190
3.4%
13 ASTHENIA 2,102
3.3%
14 MALAISE 1,924
3.0%
15 WEIGHT DECREASED 1,921
3.0%
16 PAIN 1,897
2.9%
17 FALL 1,818
2.8%
18 PNEUMONIA 1,752
2.7%
19 ARTHRALGIA 1,734
2.7%
20 OFF LABEL USE 1,686
2.6%
21 PANCREATIC CARCINOMA 1,669
2.6%
22 RASH 1,603
2.5%
23 PRODUCT DOSE OMISSION ISSUE 1,569
2.4%
24 HYPOGLYCAEMIA 1,561
2.4%
25 CONSTIPATION 1,475
2.3%
26 RENAL FAILURE 1,461
2.3%
27 ABDOMINAL PAIN 1,429
2.2%
28 COUGH 1,409
2.2%
29 ANAEMIA 1,390
2.2%
30 DECREASED APPETITE 1,377
2.1%

Important Disclaimer

FDA adverse event reports are submitted voluntarily and do not prove causation. A reported reaction does not mean the drug caused it. Drugs with more users naturally have more reports. Always consult your doctor or pharmacist before making medication decisions.